PUBLICATIONS - Cecilia
A. McIntosh
Cecilia A. McIntosh, Assistant Dean, School of Graduate
Studies and Professor, Department of Biological Sciences. (mcintosc@etsu.edu) Ph.D. University of South Florida, Tampa. Plant biochemistry; study of the
biosynthesis of flavonoids; regulation
of accumulation of specific compounds in plants; structure/function studies of flavonoid
glucosyltransferase enzymes; biotechnology.
PUBLICATIONS:
Book
Chapters and Invited Reviews:
McIntosh, Cecilia
A. (2006) “Translational Opportunities in Plant
Biochemistry”, in Integrative
Plant Biochemistry as We Approach 2010, Recent Advances in Phytochemistry, vol. 40,
J.T. Romeo (ed.), Elsevier Press, New York. (In Preparation).
McIntosh, Cecilia A. 2000.
'Quantification of Limonin and Limonoate A-ring Monolactone During
Growth and Development of Citrus
Fruit and Vegetative Tissue by Radioimmunoassay', Chapter 6 in Citrus Limonoids:
Functional chemicals in agriculture, food, flavor, and health, ed. by M.
Berhow, S. Hasegawa, and G. Manners, ACS Symposium Series. pp. 73-95.
Oliver, D.J. and C.A.
McIntosh. 1995. 'The Biochemistry of the
Mitochondrial Matrix.' in The Molecular
Biology of Plant Mitochondria, ed. by S. Levings
and I. Vasil, Kluwer
Academic Publishers, The Netherlands. pp 237-280.
Mansell, R.L. and C.A.
McIntosh. 1991. 'Citrus spp.: In Vitro
Culture and the Production of Naringin and Limonin', in Biotechnology of Medicinal and Aromatic Plants, vol. 3, ed. by
Y.P.S. Bajaj, Springer-Verlag
Berlin, Heidelberg, New York pp. 193-210.
Mansell, R.L. and C.A.
McIntosh. 1988. 'Enzyme Immunoassay of Plant
Constituents.' in Non-Isotopic
Immunoassays. ed. by T.T. Ngo, Plenum Publishing
Corp. ( New
York ) pp.
147-162.
Research Articles: (student co-authors in bold type)
RoySarkar, T., C.L. Strong, M.B. Sibhatu,
L.M. Pike, and C.A.
McIntosh. 2005. Cloning, Expression,
and Characterization of a Putative Flavonoid Glucosyltransferase from
Grapefruit (Citrus paradisi)
Leaves. In Proceedings of the 3rd International Congress on Plant Metabolomics, Iowa
State University, B. Nikolau (ed.), Elsevier Publishers (Invited submission;
In Press)
Pelt,
J., W.A. Downes, R. Schoborg, and C.A. McIntosh. 2003. Changes in Flavanone 3-Hydroxylase
(F3H) Expression During Growth and Development of Citrus paradisi and Petunia
hybrida Seedlings. Phytochemistry 64:435-444.
Owens,
D.K., T. Hale, L.J. Wilson, and C.A. McIntosh. 2002. Quantification of Dihydrokaempferol
Production by Flavanone-3-Hydroxylase using Capillary Electrophoresis. Phytochemical
Analysis 13:69-74.
Durren,
R.L. and C.A. McIntosh.
1999. Flavanone-7-O-Glucosyltransferase Activity from Petunia hybrida. Phytochemistry 52:793-798.
McIntosh , C.A.
1997. Partial
Purification and Characteristics of Membrane-Associated NAD+-Dependent
Isocitrate Dehydrogenase Activity from Etiolated Pea Mitochondria. Plant
Science 129:9-20.
McIntosh , C.A.
and R.L. Mansell.
1997. Three-dimensional
analysis of limonin, limonoate A-ring monolactone, and naringin in the fruit
of three varieties of Citrus paradisi. J.
Agric. Food Chem. 45:2876-2883.
McIntosh
C.A.
and D.J. Oliver. 1994.
The Phosphate Transporter from Pea Mitochondria: Isolation and Characterization in Proteolipid Vesicles.
Plant Physiology 105:47-52.
McIntosh , C.A. and
D.J. Oliver. 1992. NAD-Linked Isocitrate Dehydrogenase: Isolation, Purification, and
Characterization of the Protein from Pea Mitochondria. Plant
Physiology 100:69-75.
McIntosh , C.A.
and D.J. Oliver.
1992. Isolation and
Characterization of the Tri-carboxylate Transporter
from Pea Mitochondria. Plant Physiology 100:2030-2034.
McIntosh , C.A.
and R.L. Mansell. 1990. Biosynthesis of naringin in Citrus paradisi: UDP-glucosyltransferase activity in
grapefruit seedlings. Phytochemistry 29:1533-1538.
McIntosh , C.A.
, L. Latchinian, and R.L. Mansell. 1990.
Flavanone-specific O-7-glucosyltransferase activity in Citrus paradisi seedlings: Purification and characterization. Arch.
Biochem. Biophys. 282:50-57.
Barthe,
G.A., P.S. Jourdan , C.A. McIntosh,
and R.L. Mansell. 1988. Radioimmunoassay for the quantitative
determination of hesperidin in Citrus
sinensis. Phytochemistry 27:249-254.
Barthe,
G.A., P.S. Jourdan , C.A. McIntosh,
and R.L. Mansell. 1987. Naringin and limonin production in callus
cultures and regenerated plants from Citrus
sp. J. Plant Physiol. 127:55-65.
McIntosh , C.A.
, R.L. Mansell, and S. Barros. 1987.
Relationship between limonin concentration and naringin concentration
in commercial single strength grapefruit juice. J.
Food Science 52:1734-1735.
Jourdan,
P.S., C.A. McIntosh,
and R.L. Mansell. 1985. Naringin levels in Citrus tissues: II.
Quantitative distribution of naringin in Citrus paradisi Macfad. Plant
Physiology 77:903-908.
McIntosh , C.A.
and R L. Mansell.
1983. Distribution of limonin
during the growth and development of leaves and branches of Citrus paradisi. J.
Agric. Food Chem. 31:318-325.
Mansell, R.L.
, C.A. McIntosh,
and S.E. Vest. 1983. An analysis of the limonin and naringin
content of grapefruit juice samples collected from Florida
state test houses. J. Agric. Food Chem. 31:156-162.
McIntosh , C.A. ,
R.L. Mansell, and R.L. Rouseff. 1982.
Distribution of limonin in the fruit tissues of nine grapefruit
cultivars. J. Agric. Food. Chem.
30:689-692.
Abstracts
Presented and Published: (selected ones
from the last 10 years; students in bold type)
Strong, C.L., J. Cantrell,
L.M. Pike, and C.A.
McIntosh. 2005. Flavonoid Glucosyltransferases
in Citrus paradisi: Evaluation
of Putative Clones Obtained from Grapefruit Leaves using SMART RACE RT-PCR
and EST Mining. Phytochemical Society of North
America Annual Meeting, Salk Institute, La
Jolla, CA. July 2005.
Kiser, S., C.L. Strong,
L.M. Pike, and C.A.
McIntosh. 2005. EST Mining of a Putative Flavonoid Glucosyltransferase
Clone from Citrus paradisi Leaves: Cloning,
Expression, and Functional Analysis. Phytochemical Society of North America
Annual Meeting, Salk Institute, La
Jolla, CA. July 2005.
RoySarkar, T., C.L. Strong,
L.M. Pike, and C.A.
McIntosh. 2004. Cloning, Expression, and Characterization of Putative
Flavonoid Glucosyltransferases from Grapefruit (Citrus paradisi) Leaves.
Third International Congress on Plant Metabolomics,
Iowa
State
University,
Ames,
IA,
June 2004.
Bohon, L., D. Curtis, M. Dosher,
K. Edwards, J. Hamman, H. Hopson, R. Lay, T.R.
Lowe, A. Mansey, A. Martin, D. Miller, B.
Moore, A. O’Connor, J. Papy, A. Parker, T.
Powers, J. Price, C. Pritchett, K. Sanchez, J. Savage, C. Shipley, J. Sikora, S. Smith, J. Stanton, K. Taylor, J. Weaver, J.
Willis, B. Rosecrance, K. Wagner (all preceding were students in
Biology at Science Hill High School), K. Crawford (teacher), and
C. A. McIntosh. 2003. Effect of Water
Quality on Barley Seed Germination and Amylase Activity. East
Tennessee
State
University
19th
Annual
Student Research Forum, Johnson
City, TN,
April 2003.
Sibhatu, M.B.,
L.M. Pike, and C.A.
McIntosh. 2003. Cloning and Sequence Determination
of Glucosyltransferase (GT) Genes from Grapefruit Seedlings: Searching for
7-O-GT. Annual Meeting of the
Phytochemical Society of North America,
Peoria,
IL,
August 2003.
Downes,
W. A. and C.A. McIntosh. 2001.
Analysis of Grapefruit Flavanone-3-Hydroxylase (F3H) and Comparison to
Other F3H Sequences. Annual meeting of
the Phytochemical Society of North America, Oklahoma
City , OK
, August 2001.
Tanner, D.C.
and C.A. McIntosh. 2000.
Structural Elucidation of Flavanone-7-O-Glucosyltransferase from Citrus paradisi. Plant Molecular Biology Conference 2000, a
joint meeting of the Phytochemical Society of North America
and the Mid-Atlantic Plant Molecular Biology Society, Beltsville,
MD,
August 2000.
Owens, D.K.,
L.J. Wilson, and C.A. McIntosh. 2000.
Development of a Sensitive Quantitative Assay for
Flavanone-3-Hydroxylase using Capillary Electrophoresis. Plant Molecular
Biology Conference 2000, a joint meeting of the Phytochemical Society of North
America and the Mid-Atlantic Plant Molecular Biology Society, Beltsville , MD
, August 2000.
Pelt, J.L., R. Schoborg, and C.A. McIntosh. 2000.
A Comparison of Flavanone-3-O-Hydroxylase (F3H) mRNA Levels in Petunia hybrida and Citrus paradisi. Plant Molecular
Biology Conference 2000, a joint meeting of the Phytochemical Society of North
America and the Mid-Atlantic Plant Molecular Biology Society, Beltsville , MD
, August 2000.
McIntosh , C.A. 1999 'Quantification of Limonin and
Limonoate A-ring Monolactone in Citrus
by Radioimmunoassay'. ACS 217th
National Meeting, Anaheim , CA
, March 1999 (invited symposium).
Owens, D.K., Hale, T.L.T.,
Wilson , L.J., and C.A. McIntosh. 1999. Development of a Sensitive
Quantitative Assay for Flavanone 3-Hydroxylase. Association of Southeast
Biologists Annual Meeting, April 1999.
McIntosh , C.A.
1998. NAD+-Dependent Isocitrate Dehydrogenase: Characteristics of
Soluble and Membrane-Associated Forms Partially Purified from Pea
Mitochondria. Annual meeting of the
Southern Section of the American Society of Plant Physiologists, Roanoke
, VA , March 1998.
Durren,
R.L. and C.A. McIntosh.
1998. Isolation and Characterization of a Flavanone-7-O-Glucosyltransferase
Activity from Petunia hybrida. Annual meeting of the Phytochemical Society
of North America, Pullman , WA.
, July 1998.
Durren,
R. and C.A. McIntosh. 1996.
Characterization of Flavanone-7-O-Glucosyltransferase Activity in Petunia hybrida and Antirrhinum majus. Phytochemical
Society of North America
36th Annual Meeting, New
Orleans , LA.
McIntosh , C.A. 1995.
Characterization of the Membrane-Associated NAD+-Dependent
Isocitrate Dehydrogenase Activity in Pea Mitochondria. International Meeting on "Plant
Mitochondria: From Gene to Function", April 7-12, Duke
University,
Durham , North
Carolina .
(invited presentation)
Date site was last updated 01/26/2006