Center Welcomes New Member from the Chemistry Department
Dr. Abbas Shilabin, Assistant Professor of Chemistry, is the newest member of the Center of Excellence in Inflammation, Infectious Disease and Immunity. Dr. Shilabin is also the first member from the Department of Chemistry and the second from the College of Arts and Sciences.
After receiving his PhD in Organic Chemistry at the Institut fr Organische Chemie der TU Clausthal in Germany, Shilabin completed a series of Post-Doctoral Research Projects at several universities in the United States before arriving at East Tennessee State University. His work has primarily focused on Medicinal Chemistry and Pharmacognosy, or the isolation and synthesis of drugs from plants and natural sources.
Shilabin has further specialized in the field of bio-polymers and the structural modification of molecules to increase the biological activity and reduce the level of toxicity present. While at Wesleyan University in Middletown, CT, he and Dr. Rex Pratt worked to develop new non-b-lactam antibiotics targeting cell wall D,D-transpeptidases as well as discovery of novel inhibitors of b-lactamases present in bacteria with antimicrobial drug resistance. This specialization has led to breakthroughs in further understanding of the mechanisms of drug resistance, and research into anti-biotics with natural, microbial sources while at ETSU.
As a new center member, Shilabin is interested in collaborating with other center members in new drug discovery and synthesis by making use of the newly purchased Nuclear Magnetic Resonance Instrument (NMR) and drug synthesis lab.
The addition of Dr. Shilabin to the CIIDI represents a new level of collaboration across departments and colleges as part of the larger mission of the center. By recruiting strong researchers across different disciplines such as Dr. Shilabin it is hoped that the center can continue to expand areas of research expertise and potential funding streams for both the Quillen College of Medicine and the University as a whole.