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Dennis M. Defoe


Professor, Department of Biomedical Sciences

Contact Information:

Department of Biomedical Sciences
Quillen College of Medicine
PO Box 70582
Stanton-Gerber Hall, Room B213
Lab B247
Phone: 423-439-2010

Research Interests:

1.  Ocular tissue size control
2.  Taste bud regeneration
3.  Stem cell self-renewal and fate


He, Z., Forest, F., Gain, P., Rageade, D., Bernard, A., Acquart, S., Peoc’h, M., Defoe, D.M. and Thuret, G. 3D map of the human corneal endothelial cell. Sci Rep. 2016; 6:29047.

Harrison TA, He Z, Boggs K, Thuret G, Liu HX, Defoe DM. Corneal endothelial cells possess an elaborate multipolar shape to maximize the basolateral to apical membrane area. Mol Vis. 2016; 22:31-9.

Hoover JL, Bond CE, Hoover DB, Defoe DM. Effect of neurturin deficiency on cholinergic and catecholaminergic innervation of the murine eye. Exp Eye Res. 2014; 122:32-9.

Harrison TA, Smith Adams LB, Moore PD, Perna MK, Sword JD, Defoe DM. Accelerated turnover of taste bud cells in mice deficient for the cyclin-dependent kinase inhibitor p27Kip1. BMC Neurosci. 2011 Apr 20;12:34. (




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