Thomas E. Kwasigroch

Associate Dean for Student Affairs
Professor, Department of Biomedical Sciences 
Director, Programs in Human Anatomy
Director, Anatomical Gift Program
Adjunct Professor of Physical Therapy
Adjunct Professor of Clinical Anesthesia, Virginia Commonwealth University

 
Contact Information:

Department of Biomedical Sciences
James H. Quillen College of Medicine
East Tennessee State University
P.O. Box 70582
Johnson City, Tennessee 37614
Telephone No.: (423) 439-2006
Fax No.:(423) 439-2017
 

 


4335 Summerfield Drive
Piney Flats, TN 37686
Telephone No.: (423) 289-9801


Education:

B.S.   Niagara University, 1967 ( Biology)
Ph.D.   University of Virginia, 1976 ( Anatomy/Embryology)
Postdoctoral
Fellowship:
  Institute für Toxikologie und Embryonalpharmakologie, Freie Universitat Berlin, West Germany (1975 1979)
 

Professional Experience

1979 - 1984   Assistant Professor: Department of Anatomy, James H. Quillen College of Medicine
1984 - 1992   Associate Professor: Department of Anatomy, James H. Quillen College of Medicine
1992 - Present   Professor: Department of Biomedical Sciences, James H. Quillen College of Medicine
1996 - Present   Adjunct Professor, Department of Physical Therapy, East Tennessee State University
2000 - 2005   Assistant Dean for Curriculum
2005 - Present   Associate Dean for Student Affairs
 

Research Experience/Interests:

1967 - 1968   Veterans Administration Hospital, Syracuse, New York. Technician in cancer research. Investigation of the electric potential difference between cancerous and normal human tissues and the effect of varying levels of electrical current on the activities of tumorigenic cells in culture.
1972 - 1975   Department of Anatomy, University of Virginia, Charlottesville, Virginia. Predoctoral research. Investigation of normal and retinoic acid) altered limb development in mouse embryos including in vitro examination of cell migration, adhesion and proliferation of limb mesenchyme. Dissertation "The behavior of embryonic cells in culture: Effect of excess vitamin A on limb bud cells in vivo and in vitro."
1976 - 1979   Institut für Toxikologie und Embryonalpharmakologie, Freie Universitat, Berlin, West Germany. Postdoctoral fellow. Investigation of myogenesis in limb buds of normal and teratogen treated mouse embryos, to include: investigation of temporal appearance and isoenzyme profile of the "muscle specific" enzyme creatine kinase in in vivo and in vitro developed mouse limb buds, and isolation and purification of skeletal muscle myosin for preparation of antimyosin antibodies for use in immunofluorescent and radio immune assay techniques. Development of a submerged limb bud culture system.
1979 - 1994   Department of Anatomy, James H. Quillen College of Medicine. Investigation of growth, cytodifferentiation and morphogenesis of limbs and limb mesenchyme grown in vivo and in vitro and the effects of drugs on toxic compounds upon these and related cellular phenomena. Studies on the mechanisms of action of retinoic acid and its metabolites. Use of computerized optical image analysis for evaluation of congenital defects. Evaluation of drug interactions on adverse pregnancy outcome.
2000 - Present   Integration of clinical and basic sciences in medical education. “How can a curriculum maximally assist students with the development of their clinical skills”.
 
East Tennessee State University Faculty Instructor:
Director, Electives Programs in Medical Human Gross Anatomy (1985 - Present)
USMLE I Review Presentations in Gross Anatomy and Embryology (1985 - Present)
Director, The Human Body Course for Medical Students (1985 - Present)
Director, The Human Body Course for Physical Therapy Students (1995 - Present)
Director, Anatomy for Clinical Registered Nurse Anesthetists (2005 – Present)
 

Professional Activities

Major Committees And University Services

Current   College of Medicine Executive Committee (2005 – Present)
Medical Student Advisor ( 1980 - Present)
Present Member, Graduate Faculty (1980 Present)
Senior Electives Committee, Basic Science Representative (1986 Present)
ROTC Advisory Board Member (1987 Present)
Department of Anatomy Executive Committee (1992 Present)
Medical Student Education Committee (1993 Present)
Admissions Committee (1993 Present)
Admissions Committee, Physical Therapy Program (1994 Present)
Chair, Basic Science Integration Subcommittee (1996 Present)
Intercollegiate Athletics Committee (2001 - Present)
Student Promotions Committee (2000 - Present)
RPCT Interdisciplinary Curriculum Committee (2002 - 2006)
 
Current Professional Organizations

Teratology Society
Alpha Omega Alpha


Selected Professional Honors

August, 1982   James H. Quillen College of Medicine, "Faculty Honor Roll" for excellence in instruction.
August, 1983   James H. Quillen College of Medicine, "Faculty Honor Roll" for excellence in instruction.
June, 1984   James H. Quillen College of Medicine, "Faculty Honor Roll" for excellence in instruction.
May, 1985   Honored by the Class of 1985 as the Faculty Member selected to award MD hoods at graduation exercises.
August, 1985   Professor of the Year, James H. Quillen College of Medicine.
March, 1987   Selected for Membership on NIH Clinical Sciences Study Section #3
May, 1987   Honored by the Class of 1987 as the Faculty Member selected to award MD hoods at graduate exercises.
August, 1987   Selected for membership in National Medical Honor Society, Alpha Omega Alpha.
August, 1988   Professor of the Year, James H. Quillen College of Medicine
May, 1988   Honored by the Class of 1988 as the Faculty Member selected to award MD hoods at graduate exercises.
March, 1989   Selected for Membership on NIH Physiological Sciences Study Section
August, 1989   Professor of the Year, James H. Quillen College of Medicine
December, 1989   Johnson City Parks and Recreation "Outstanding Service Award"
June, 1989   Elected Chairman, Publications Committee and Editorial Review Board, TERATOLOGY
May, 1995   Honored by the Class of 1995 as the Faculty Member selected to award MD hoods at graduation exercises
August, 1995   Professor of the Year, James H. Quillen College of Medicine
June, 1991   Elected Chairman, Membership Committee, Teratology Society
March, 1991   Appointed to NIH Reserve Pool of Peer Reviewers
1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2000   Dean's Award for Excellence in Teaching (Originated in 1992, ended 2000)
December 1994   Honored by the Class of 1994 as the Faculty Member to award MD hoods at graduation exercises
May, 1996   Outstanding Faculty Award
August, 1996   Lee Brashear's Memorial Award for Excellence in Teaching and Student Support
May, 1997   James H. Quillen College of Medicine Distinguished Teaching Award
May, 1997   American Medical Woman's Association, Gender Equity Award
April, 1999   Professor of the Year, 1998

Course of the Year, 1998-1999; Awarded to Director, Medical Human Gross Anatomy, (Award Originated April, 1999)

College of Medicine Department of the Year, 1998-1999 (Award Originated April, 1999)

May, 1999   Honored by the Class of 1999 as the Faculty Member selected to award MD hoods at graduation exercises
September, 1999   Professor of the Year, 1998-1999
March, 2000   Course of the Year, 1999-2000; Awarded to Director, Medical Human Gross Anatomy

College of Medicine Department of the Year, 1999-2000
May, 2000   Honored by the Class of 2000 as the Faculty Member to award MD hoods at graduation exercises
April, 2001   Lee Brashear’s Memorial Award for Excellence in Teaching and Student Support

Course of the Year, 2000-2001; Awarded to Director, Medical Human Gross Anatomy
April 2003   Professor of the Year, 2002-2003

Course of the Year, Awarded to Director, The Human Body
April 2004   Professor of the Year, 2003-2004

Course of the Year, 2003-2004, Awarded to Director, The Human Body

Scarlet Sash Recipient
May 2004   Honored by Class of 2004 as the Faculty Member to award MD hoods at graduation exercises.

Nominated by College of Medicine for the AOA Robert J. Glaser Distinguished Teachers Award
April 2005   Professor of the Year, 2004-2005

Course of the Year, 2004-2005, Awarded to Director, The Human Body

Scarlet Sash Recipient

Received the national “Joy McCann Foundation Scholars Award” for mentoring
April 2006   Professor the Year, 2005-2006
Course of the Year, 2005-2006
Scarlet Sash Recipient
 

Military Service

1968 - 1969 Officer Candidate School and Airborne Course Ft. Benning, Georgia. 2nd Lt., Instructor, 6th Special Forces Group Ft. Bragg, North Carolina.
1969 - 1970 1st Lt., Infantry Platoon Leader, Company Executive Officer and Battalion Liaison Officer Republic of Viet Nam.
1970 - 1971 Executive Officer, Medical Support Company Ft. Bragg, North Carolina.
1971 - 1974 U.S. Army Reserve.
1974 Honorable Discharge.
 

Military Awards

Bronze Star Viet Nam Campaign Medal
Purple Heart Good Conduct Medal
Army Commendation Medal Letter of Commendation for Excellence in Military Instruction
 

Community, Church, And Other Activities

1980 - 1987   Coordinator of College of Medicine Intramural Athletics
1983 - 2000   Johnson City Parks and Recreation Youth Soccer Coach
1984 - 1985   Johnson City Boy's Club Youth T Ball Coach
1984 - 1985   St. Mary's Church Parish Pastoral Council and Youth Ministry Coordinator
1985 - 1987   Chairperson, St. Mary's Church Parish Council
1985 - 1990   Johnson City Boy's Club Youth Basketball Coach
1985 - 1990   Coach, Johnson City Little League
1986 - 2000   Board Member, East Tennessee Soccer Federation
1986 - 2000   Tennessee Youth Soccer Association, Certified Referee
1988 - 1990   Board Member, Hamilton Bank Invitational Soccer Tournament Committee
1988 - 1990   Coach, Johnson City Parks and Recreation Youth Basketball
1991 - 1995   Head Soccer Coach, University High School
Current   Grammar School Enrichment Program Participant (1984 - Present)

Who's Who in America (1992 - Present)

Presenter, Rural Health Career Fair (1996 - Present)

Active competitor in participant sports such as running, basketball, soccer, golf, canoeing, hiking, skiing, biking (Present)
Other Interests   Reading, Travel, Arts, Symphony
 

Publications:

Books
Methods in Prenatal Toxicology. Evaluation of Embryotoxic Effects in Experimental Animals.
1977, (Eds., D. Neubert, H. J. Merker and T.E. Kwasigroch), Georg Thieme Publishers, Stuttgart.
Refereed Papers
Kwasigroch, T.E. and D.M. Kochhar, 1975. Locomotory behavior of limb bud cells: the effect of excess vitamin A in vivo and in vitro. Exp. Cell Res. 95: 269 278.
Kwasigroch, T.E., H. J. Barrach, S. Tapken, M. Rautenberg and D. Neubert, 1977.
Submerged culture of mammalian limb buds. In: Advances in the Detection of Congenital Malformations. (eds. E.B. van Julsingha, J.M. Tesh and G.M. Fara), Michael Robbin Prainters, Chelmsford, Essex, England, pp. 257 263.
Kwasigroch, T.E., 1977. Culture of tissue fragments and cells at high density. In: Methods in Prenatal Toxicology. Evaluation of Embryotoxic Effects in Experimental Animals. (Eds. D. Neubert, H. J. Merker and T.E. Kwasigroch), Georg Thieme Publishers, Stuttgart, pp. 263 272.
Chahoud, I. and T.E. Kwasigroch, 1977. Controlled breeding of laboratory animals. In: Methods in Prenatal Toxicology. Evaluations of Embryotoxic Effects in Experimental Animals. (Eds. D. Neubert, H. J. Merker and T.E. Kwasigroch), Georg Thieme Publishers, Stuttgart, pp. 78 91.
Kwasigroch, T.E. and D. Neubert, 1978. A simple method to test chondrogenic and myogenic tissues for differential effects of drugs. In: Role of Pharmacokinetics in Pre and Perinatal Toxicology (Eds. D. Neubert, H. J. Merker, H. Nau and J. Langman), George Thieme Publishers, Stuttgart, pp. 621 629.
Kwasigroch, T.E. and D.M. Kochhar, 1980. Vitamin A alters the adhesiveness of limb bud mesenchymal cells. J. Embryol. Exp. Morph. 59: 325 339.
Kwasigroch, T.E. and D.M. Kochhar, 1980. Production of congenital limb defects with retinoic acid: Phenomenological evidence of progressive differentiation during limb morphogenesis. Anat. Embryol. 161: 105 113.
Peppler, R.D., M.W. Hougland, T.E. Kwasigroch, and R.G. Skalko, 1980. Medical gross anatomy course: Simultaneous teaching of the upper and lower extremity. J. Med. Educ. 5 5: 794 796.
Kwasigroch, T.E. and D. Neubert, 1980. Estimation of creatine phosphokinase and hydroxyproline in the developing limb: its use in evaluating the effect of teratogens on myogenesis and chondrogenesis. Teratog. Carcinog. Mutagen. 1: 181 191.
Skalko, R.G. and T.E. Kwasigroch, 1980. An analysis of the asymmetric response of the eveloping limb to embryotoxic agents. In: Teratology of the Limbs (Eds. H. J. Merker, H. Nau and D. Neubert), Walter de Gruyter and Co., Berlin, pp. 295 300.
Kwasigroch, T.E., R.G. Skalko, and J.K. Church, 1981. Development of limb buds in organ culture: Examination of hydroxyurea enhancement of bromodeoxyuridine toxicity using image analysis. In: Culture Techniques. Applicability for Studies on Prenatal Differentiation and Toxicity.(Eds . Neubert and H. J. Merker), Walter de Gruyter and Co., Berlin, pp. 237 253.
Kwasigroch, T.E. and R.G. Skalko, 1983. Development of mouse limb buds in organ culture: Dose dependent retinoic acid induced defects evaluated using image analysis. In: Limb Development and Regeneration, Part A. (Eds. J.F. Fallon and A.I. Caplan), Alan R. Liss, New York, pp. 335 344.
Skalko, R.G. and T.E. Kwasigroch, 1983. The interaction of chemicals during pregnancy: An update. Biol. Res. Preg. Perinatol. 4: 26 35.
Peppler, R.D., T.E. Kwasigroch, and M.W. Hougland, 1983. Cross sectional anatomy: preparation of teaching specimens. Anat. Rec. 206: 341 344.
Skalko, R.G., P.D. Poche, and T.E. Kwasigroch, 1984. The toxicology of chemical interaction during pregnancy in the mouse: caffeine and phenytoin. Toxicol. 30: 7 16.
Kwasigroch, T.E. and R.G. Skalko and J.K. Church, 1984. Mouse limb bud development in submerged culture: quantitative assessment of the effects of in vivo exposure to retinoic acid. Teratog. Carcinog. Mutagen. 4: 311 326.
Kwasigroch, T.E. and R.G. Skalko, 1984. Estimation of creatine kinase isoenzymes: the effects of caffeine and retinoic acid on CK levels in fetal mouse limbs. Toxicol. Lett. 21: 339 347.
Skalko, R.G. and T.E. Kwasigroch, 1985. The use of submerged limb culture and image analysis for evaluating retinoic acid induced dose related effects. In: Prevention of Physical and Mental Congenital Defects, Part C: Basis and Medical Science Education and Future Strategies. (Eds. M. Marois) Alan R. Liss, New York, pp. 115 120.
Peppler, R.D., T.E. Kwasigroch and M.W. Hougland, 1985. Simultaneous teaching of the upper and lower extremities in Medical Gross Anatomy: A four year follow up and correlation with NBME 1 performance. J. Med. Educ. 60: 635 639.
Kwasigroch, T.E. and R.G. Skalko, 1985. The teratogenic interaction of hydroxyurea and 5 bromodeoxyuridine examined with the aid of limb culture and image analysis. Fundam. Appl. Toxicol. 5: 1161 1173.
Kwasigroch, T.E., J.F. Vannoy, J.K. Church and R.G. Skalko, 1986. Retinoic acid enhances and depresses in vitro development of cartilaginous bone anlagen in embryonic mouse limbs. In Vitro Cell Dev. Biol. 22: 150 156.
Elmer, W.A., M.F. Pennybacker, T.B. Knudsen and T.E. Kwasigroch, 1988. Alterations in cell surface glycosyltransferase in Brachypod mutant mouse embryos. Teratology 38:475 484.
Kwasigroch, T.E. and M. Bullen, 1991. Effects of 13 cis retinoic acid (Isotretinion) on the development of mouse limbs in vivo and in vitro. Teratology A4: 605 616.
Kwasigroch, T.E., S.K. Curtis, T.B. Knudsen, H. J. Barrach, and W.A. Elmer. 1992. Morphological analysis of abnormal digital chondrogenesis in the brachypod (be) mouse limb in organ culture. Anatomy and Embryology 185: 307 315.
Elmer, W.A., E.I. Egozi, S. Pollard, Jr., J.D. Cochran, and T.E. Kwasigroch, 1993. Glycosidic cleavage of galactose from chick limb mesenchymal cells inhibits in vitro chondrogenesis. In: Limb Development and Regeneration. Wiley Liss, pp. 445 454.