Dr. Barbara B. Turner

Professor Emeritus

Dr. Turner

Education:
B.A. (Biology) 1967 Immaculate Heart College, Los Angeles, CA
M.A. (Biology) 1970 Immaculate Heart College, Los Angeles, CA
Ph.D. (Neuroscience) 1974 University of California, Los Angeles, CA


Recent Academic Appointments:

1993 - Present Professor, East Tennessee State University,
James H. Quillen College of Medicine,
Department of Biomedical Sciences, Johnson City, TN
1989 - Present Adjunct Associate Professor / Professor,
Department of Psychiatry,
East Tennessee State University
James H. Quillen College of Medicine,
Johnson City, TN


Research Interests:

Research interests are centered in the area of neuroendocrinology.  Our past studies have shown the existence of gender differences in the brain corticosteroid receptors involved in regulating stress responses and also the influence of stress and gonadal steroids on the development ofarthritis.  We are continuing work on the role of brain mineralocorticoid receptors in modulating expression of the serotonin 1A receptor, a key target of anti-depressants. We have already shown that both the mineralocorticoid receptor mRNA and the serotonin 1A receptor mRNA are altered by changes in photoperiod.  The main focus of the laboratory is moving in a more molecular direction: looking at protein-protein interactions between corticosteroid receptors and their co-regulators.  We are currently beginning work to define the co-activators and co-repressors that regulate transactivation by the mineralocorticoid receptor.

Recent Publications:

Miller, S.C., S.H. Rapier, L.I. Holtsclaw and B.B. Turner. Effects of psychological stress on joint inflammation and adrenal function during induction of arthritis in the Lewis rat.  NeuroImmunoModulation 2:329-338, 1995.

Turner, B.B.  Influence of gonadal steroids on brain corticosteroid receptors:A mini-review.  Neurochem. Res. 22:1372-85, 1997.

Lance,S.J.,S.C.Miller,L.I.Holtsclaw,B.B.Turner.  Photo-period regulation of mineralocorticoid receptor mRNA expression in hamster hippocampus. Brain Research (780:342-347, 1998).

Recent Abstracts:

Turner, B.B., T. Hunter, R.R. Holson, and S.A. Ferguson.  Dexamethasone treatment on postnatal day 7: Effects on adrenal function in rats as adults.  Abstracts of the 80th Annual Meeting of the Endocrine Society, June, 1998.

Turner, B.B., S.C. Miller, S.H. Rapier, and M. Farid.  Thymocyte Survival in Collagen-Induced Arthritis and Chronic Stress: Correlation with Glucocorticoid Receptor and CRH ir.   Abstracts of the 81st Annual Meeting of the Endocrine Society, June 1999.

Turner, B.B., T Hunter, M.Farid, R.R. Holson, and S.A. Ferguson. Dexamethasone Treatment on Postnatal Day 7: Effects on brain corticosteroid Receptors and Plasma Binding Proteins in Rats as Adults.  Neurosci. Abstracts 25:455, 1999.

Turner, B.B., Bibbs, R.K., Flynn, K.M., Ferguson, S.A., Newbold, R.R., and Turner, B.B.  Effect of Dietary Genistein on Circulating Levels of Sex Steroids: A Multi-Generational Study in Male Rats.    Abstracts of the 82nd Annual Meeting of the Endocrine Society, June 2000.

Tanner, D.C., and Turner, B.B. Effect of Daylength on the Expression of Serotonin-1A Receptors in the Hamster Hippocampus.  Neurosci. Abstracts 26:121, 2000.

Mail Address:
Department of Biomedical Sciences 
James H. Quillen College of Medicine
East Tennessee State University
P. O. Box 70582
Johnson City, TN 37614
Email:
Voice: 423-439-2043
Fax: 423-439-2052

Street Address:

Department of Biomedical Sciences
James H. Quillen College of Medicine
East Tennessee State University
Stanton-Gerber Hall Room B135
Maple Avenue
Mountain Home, TN 37684