Xuefeng Liu

Xuefeng Liu
Assistant Professor
Phone: (423) 439-4478
Email:   lix01@etsu.edu
Office:  Lamb Hall, Room 149H


Education

Ph.D. in Statistics (2006) Department of Statistics, University of Florida
Dissertation Title: Methodology for Models with Multivariate (Longitudinal) Outcomes

M.S. in Statistics (2002) Department of Statistics, University of Florida

M.S. in Classical Statistical Genetics (1993) Department of Agronomy, Yangzhou University, China


Courses Taught
  • PUBH5310-904: Biostatistics I online (Fall and Summer)
  • PUBH5360-201: Experimental Design and Analysis (Spring)
  • PUBH5310-201: Biostatistics I (Fall)

Research Focus
  • MCMC algorithms, Bayesian statistics, computational statistics
  • Repeated measures models, latent variable models, latent class/trait models, multi-level models, Covariance models, missing data models
  • Design and analysis of clinical trials
  • Statistical methodologies for epidemiology, genetics, cardiovascular disease, kidney function, diabetes, hypertension, cancer, etc.

Selected Publications
  1. Xuefeng Liu, Yali Liu, Dennis Tsilimingras. Associations of Microalbuminuria and Macroalbuminuria with the Prevalence of Hypertension in Non-Hispanic Whites, Non-Hispanic Blacks and Hispanics. 2011 (Submitted).
  2. Ke-Sheng Wang, Xuefeng Liu, Longyang Wu, Zeng Min. Meta-Analysis of Genome-Wide Association Data Identifies Four Loci Influencing Formal Thought Disorder in Schizophrenia. 2011 (Submitted).
  3. Shimin Zheng, Gupta AK, Xuefeng Liu. Multivariate and Matrix Variate Skew t-distribution and Skew Pearson Type VII Distribution. Journal of Multivariate Analysis 2011 (Under revision).
  4. Ke-Sheng Wang, Xuefeng Liu, Jerald E. Mullersman, Qun-Yuan Zhang. Genome-Wide Association Analysis Identifies Novel Loci for Early-Onset Amyotrophic Lateral Sclerosis. 2011 (Under revision).
  5. Xuefeng Liu, Kesheng Wang, Dennis Tsilimingras. Racial Difference in the Association of Albuminuria with Uncontrolled BP among Adults with Diagnosed Hypertensions. 2011 (Submitted).
  6. Wang KS, Xuefeng Liu, Zhang QY, Aragam N, Pan Y. Parent-of-origin effects of FAS and PDLIM1 in attention-deficit hyperactivity disorder. Journal of Psychiatry and Neuroscience 2012; 37(1):46-52
  7. Wang KS, Xuefeng Liu, Qunyuan Zhang, Zeng, Min, Longyang, Wu. Genome-Wide Association Study Identifies 5q21 and 9p24.1 (KDM4C) Loci Associated with Alcohol Withdrawal Symptoms. Journal of Neural Transmission 2011 (Epub ahead of print)
  8. Ke-Sheng Wang, Xuefeng Liu, Qunyuan Zhang, Yue Pan, Nagesh Aragam, Min Zeng. A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. Journal of Psychiatric Research 2011; 45(11):1419-1425
  9. Tiejian Wu, Wallace E. Dixon, Jr., William T. Dalton, Fred Tudiver, Xuefeng Liu. Joint Effects of Child Temperament and Maternal Sensitivity on the Development of Childhood Obesity. Maternal and Child Health Journal 2011; 15(4):469-477.
  10. Wang KS, Xuefeng Liu, Zhang QY, Aragam N, Pan Y. Genome-wide association analysis of age at onset in Schizophrenia in a European-American sample. American Journal of Medical Genetics. Part B. Neurophychiatric Genetics 2011; 156(6):671-680.
  11. Wang KS, Xuefeng Liu, Aragam N, Jian XQ, Mullersman JE, Liu YL, Pan Y. Family-Based Association Analysis of Alcohol Dependence in the COGA Sample and Replication in the Australian Twin-Family Study. Journal of Neural Transmission 2011; 128(9):1293-1299.
  12. Xuefeng Liu, Meng Liu, Dennis Tsilimingras, Ernesto Schiffrin. Racial Disparities in Cardiovascular Risk Factors among Diagnosed Hypertensive Subjects. Journal of the American Society of Hypertension 2011; 5(4):239-248.
  13. Lee, Keunbaik, Kang, Sanggil, Xuefeng Liu, Daekwan Seo. Likelihood-based Approach for Analysis of Longitudinal Nominal Data Using Marginalized Random Effects Models. Journal of Applied Statistics 2011; 38(8):1577?1590.
  14. Xuefeng Liu, Kesheng Wang, Keunbaik Lee. The Association of Standardized Estimated Glomerular Filtration Rate with the Prevalence of Hypertension in Adults in the United States. Journal of Human Hypertension 2011; 25(8):469-475.
  15. Kesheng Wang, Xuefeng Liu, Nagesh Aragam. A Genome-Wide Meta-Analysis Identifies Novel Loci Associated with Schizophrenia And Bipolar Disorder. Schizophrenia Research 2010; 124(1-3):192-199.
  16. Mary Baker, Joel Hillhouse, Xuefeng Liu. The Effect of Initial Indoor Tanning with Mother on Current Tanning Patterns. Archives of Dermatology 2010; 146(12):1427-1428.
  17. Ke-Sheng Wang, Jerald E. Mullersman, Xuefeng Liu. Family-Based Association Analysis of MAPT Gene in Parkinson Disease. Journal of Applied Genetics 2010; 51(4):509-514.
  18. Wang KS, Liu XF, Aragam N, Jian XQ, Mullersman JE, Liu YL, Pan Y. Polymorphisms in ABLIM1 are Associated with Personality Traits and Alcohol Dependence. Journal of Molecular Neuroscience 2011 May 6; DOI: 10-1007/s12031-011-9530-6 [Epub ahead of print].
  19. Xuefeng Liu, Michael Daniels. Joint Models for the Association of Longitudinal Binary and Continuous Processes with Application to a Smoking Cessation Trial. Journal of the American Statistical Association 2009; 104:429-438.
  20. Jing Liu, Wanzer Drane, Xuefeng Liu, Tiejian Wu. Examination of the Relationships between Environmental Exposures to Volatile Organic Compounds and Liver Function Tests: Application of Canonical Correlation Analysis. Environment Research 2009; 109(2):193-199.
  21. Xuefeng Liu. Parameter Expansion for Sampling a Correlation Matrix: an Efficient GPX-RPMH Algorithm. Journal of Statistical Computation and Simulation 2008; 78(11):1065-1076.
  22. Samar Nasser, Zongshan Lai, Shannon O?Connor, Xuefeng Liu, and John Flack. Does Earlier Attainment of Blood Pressure Goal Translate Into Fewer Cardiovascular Events? Current Hypertension Reports 2008; 10(6): 398-404.
  23. Xuefeng Liu, Jeffrey Roth. Development and Validation of an Infant Morbidity Index Using Latent Variable Models. Statistics in Medicine 2008; 27(7): 971-989.
  24. Bilian Jin, Qian Tao, Jinrong Peng, Hui Meng Soo, Wei Wu, Jianming Ying, C. Robert Fields, Amber L. Delmas, Xuefeng Liu, Jingxin Qiu, Keith D. Robertson. DNA Methyltransferase 3B (DNMT3B) Mutations in ICF Syndrome Lead to Altered Epigenetic Modifications and Aberrant Expression of Genes Regulating Development, Neurogenesis, and Immune Function. Human Molecular Genetics 2008; 17(5): 690-709.
  25. Xuefeng Liu, and Jeffrey Roth. A Class of Latent Variable Models with an Application to Development of an Infant Morbidity Index. Proceedings of the American Statistical Association 2007:S458-66.
  26. John M. Flack, Karl Duncan, Suzanne E. Ohmit, Ruth Quah, Xuefeng Liu, Preeti Ramappa, Sandra Norris, Lowell Hedquist, Amanda Dudley, Samar A. Nasser. Influence of Albuminuria and Glomerular Filtration Rate on Blood Pressure Response to Antihypertensive Drug Therapy. Vascular Health and Risk Management 2007; 3(6):1029-37.
  27. Xuefeng Liu, Michael Daniels. A New Efficient Algorithm for Sampling a Correlation Matrix Based on Parameter Expansion and Re-parameterization. Journal of Computational and Graphical Statistics 2006; 15(4):897-914.

Research Projects
2010-2012 Principal Investigator, "Impact of Physical Activity on the Association between Weight Change and Smoking Cessation". NIH, R03 (To be resubmitted).
2010-2015 Co-investigator, "Cancer Screening Practices of Primary Care Providers in Appalachia". NIH/NCI, R01. PI: Amal Khoury (Resubmited).
07/2010-6/2011 Co-investigator, "Gender difference and parental influence in genetic association analysis of alcohol dependence in the COGA sample". PI: Kesheng Wang. RDC Major Research Grant (internal grant at ETSU), Total direct costs: $9,960.00
05/2009-04/2012 Principal Investigator, "Impact of Physicians? Clinic Decision on the Rapidity of Blood Pressure Goal Attainment". NIH/NHLBI (Rejected)
09/2009-08/2013 Co-investigator, "Child temperament, Parenting Style, and Childhood Obesity Risk". HRSA. PI: Tiejian Wu (Rejected)
09/2009-8/2012 Co-investigator, "Southern Appalachian Tele-Homecare Program". HRSA, H2AIT16637. PI: Karen S Cober and subcontract PI: Amal Khoury. Total Direct Cost: $167,858.00
07/2009-6/2010 Principle Investigator, "Impact of Clinic Decision on the Rapidity of Blood Pressure Goal Attainment". RDC Major Research Grant (internal grant at ETSU), Total direct costs: $10,000.00
07/2004-6/2010 Co-investigator (09-10), "Coordinated School Health Evaluation Program". Tennessee Dept. of Education. PI: Deborah Slawson. Total direct costs: $2,031,304.00
05/2003-4/2008 Biostat core faculty (50% effort, 06-08), "The Center for Urban African American Health". NIH/NIEHS, P50 ES012395. PI: John M. Flack. Total direct costs: $5,946,924.00
08/2004-7/2008 Statistics Analyst, "Analyzing complex longitudinal data in behavior science". NIH, R01 HL079457. Direct costs: $180,000.00, subcontract from Brown University, PI: Michael Daniels on subcontract
Personal Interests

Music, Basketball, Ping pong and Tennis