Xuefeng Liu

 

Xuefeng Liu
Associate Professor
Phone: (423) 439-4478
Email:  
Office:  Lamb Hall, Room 149H


Education

Ph.D. in Statistics (2006) Department of Statistics, University of Florida
Dissertation Title: Methodology for Models with Multivariate (Longitudinal) Outcomes

M.S. in Statistics (2002) Department of Statistics, University of Florida

M.S. in Classical Statistical Genetics (1993) Department of Agronomy, Yangzhou University, China


Courses Taught
  • BSTA 5310: Biostatistics I
  • BSTA 5360: Experimental Design and Analysis
  • BSTA 5310: SAS Programming with Research Application in Public Health
  • PUBH 5907: Longitudinal Models (Independent Study)

 

Awards and Honors

  • College Foundation Research Award - College of Public Health, East Tennessee State University, August 2012
  • College of Public Health Banner Carrier for Commencement, College of Public Health, East Tennessee State University, 2013
  • Dean's Recognition for Outstanding Contribution for Public Health (Presented to CSH Team), College of Public Health, East Tennessee State University, 2010
  • CLAS Travel Award for summer travel, College of Liberal and Art Sciences, University of Florida, June 2005
  • National Science Scholarship Award, China Scholarship Council (CSC) affiliated with the Ministry of Education, Beijing, China, 1998
  • College Award for Teaching Excellence, Qingdao Agricultural University, China, 1995

Research Focus
  • MCMC algorithms, high-dimensional data analysis, Bayesian statistics, computational statistics
  • Repeated measures/longitudinal models, latent variable models, latent class/trait models, multi-level models, covariance models, missing data models
  • Design and analysis of clinical trials
  • Statistical methodologies for hypertension, cardiovascular disease, genetics, diabetes, cancer, kidney function, etc.

Selected Publications

  1. Xuefeng Liu, Khoury A, Longcoy J, Ikekwere J. Grade 2 and 3 obesity and diagnosed prostate cancer in middle-aged and elderly men. ISRN Epidemiology Volume 2014 (2014), Article ID 715939, 7 pages.  Accessed by http://dx.doi.org/10.1155/2014/715939.
  2. Xuefeng Liu, Wang KS, Wang L, Tsilimingras D. Micoralbuminuria, macroalbuminuria and uncontrolled blood pressure among diagnosed hypertensive patients: the aspect of racial disparity in the NHANES study. Hypertension Research 2013; 36(12):1100-1106.Accessed by http://www.readcube.com/articles/10.1038/hr.2013.87.
  3. Xuefeng Liu, Song P. Does higher prevalence of diabetes indicate stronger association with uncontrolled blood pressure in Mexican and black diagnosed hypertensive adults? American Journal of Hypertension 2013; 26(11):1328-1334.  Accessed by http://ajh.oxfordjournals.org/content/early/2013/07/15/ajh.hpt109.full.pdf.
  4. Xuefeng Liu, Liu Y, Tsilimingras D Campbell KM. Racial disparity in the associations of microalbuminuria and macroalbuminuria with odds of hypertension: results from the NHANES study in the United States. ISRN Hypertension Volume 2013 (2013), Article ID 390109, 8 pages. Accessed by http://dx.doi.org/10.5402/2013/390109.
  5. Wang KS, Xuefeng Liu, Zhang QY, Zeng M. ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies. Drug and Alcohol Dependence 2012; 124(3): 325-332.
  6. Zheng S, Gupta AK, Xuefeng Liu. A matrix variate generalization of the skew pearson type VII and skew T distribution. Mathematical Sciences Research Journal 2013; 16(6):136-156.
  7. Wang KS, Xuefeng Liu, Zhang QY, Aragam N, Pan Y. Parent-of-origin effects of FAS and PDLIM1 in attention-deficit hyperactivity disorder. Journal of Psychiatry and Neuroscience 2012; 37(1):46-52
  8. Wang KS, Xuefeng Liu, Qunyuan Zhang, Zeng, Min, Longyang, Wu. Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms. Journal of Neural Transmission 2012; 119(4):425-433.
  9. Wang KS, Xuefeng Liu, Zhang Q, Pan Y, Aragam N, Zeng M. A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. Journal of Psychiatric Research 2011; 45(11):1419-1425. Accessed by http://www.sciencedirect.com/science/article/pii/S002239561100121X.
  10. Wu T, Dixon WE, Jr., Dalton WT, Tudiver F, Xuefeng Liu. Joint effects of child temperament and maternal sensitivity on the development of childhood obesity. Maternal and Child Health Journal 2011; 15(4):469-477. Accessed by http://www.ncbi.nlm.nih.gov/pubmed/20358395.
  11. Wang KS, Xuefeng Liu, Zhang QY, Aragam N, Pan Y. Genome-wide association analysis of age at onset in Schizophrenia in a European-American sample. American Journal of Medical Genetics. Part B. Neurophychiatric Genetics 2011; 156(6):671-680.
  12. Wang KS, Xuefeng Liu, Aragam N, Jian XQ, Mullersman JE, Liu YL, Pan Y. Family-based association analysis of alcohol dependence in the COGA sample and replication in the Australian twin-family study. Journal of Neural Transmission 2011; 128(9):1293-1299.
  13. Xuefeng Liu, Liu M, Tsilimingras D, Schiffrin EL. Racial disparities in cardiovascular risk factors among diagnosed hypertensive subjects. Journal of the American Society of Hypertension 2011; 5(4):239-248. Accessed by http://www.sciencedirect.com/science/article/pii/S1933171111000957.
  14. Lee K, Kang S, Xuefeng Liu, Seo D. Likelihood-based approach for analysis of longitudinal nominal data using marginalized random effects models. Journal of Applied Statistics 2011; 38(8):1577?1590. Accessed by http://publichealth.lsuhsc.edu/Faculty_Pages/lee/papers/Nominal_MREM_JAS.pdf.
  15. Xuefeng Liu, Wang K, Lee K. The association of standardized estimated glomerular filtration rate with the prevalence of hypertension in adults in the United States. Journal of Human Hypertension 2011; 25(8):469-475.
  16. Wang K, Xuefeng Liu, Aragam N. A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. Schizophrenia Research 2010; 124(1-3):192-199. Accessed by http://www.sciencedirect.com/science/article/pii/S0920996410015318.
  17. Baker KM, Hillhouse J, Xuefeng Liu. The effect of initial indoor tanning with mother on current tanning patterns. Archives of Dermatology 2010; 146(12):1427-1428.
  18. Wang KS, Mullersman JE, Xuefeng Liu. Family-based association analysis of MAPT gene in parkinson disease. Journal of Applied Genetics 2010; 51(4):509-514.
  19. Wang KS, Xuefeng Liu, Aragam N, Jian XQ, Mullersman JE, Liu YL, Pan Y. Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence. Journal of Molecular Neuroscience 2011 May 6; DOI: 10-1007/s12031-011-9530-6 [Epub ahead of print].
  20. Xuefeng Liu, Daniels M. Joint models for the association of longitudinal binary and continuous processes with application to a smoking cessation trial. Journal of the American Statistical Association 2009; 104:429-438. Accessed by http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746699.
  21. Liu J, Drane JW, Xuefeng Liu, Wu T. Examination of the relationships between environmental exposures to volatile organic compounds and liver function tests: Application of canonical correlation analysis. Environment Research 2009; 109(2):193-199.
  22. Xuefeng Liu. Parameter expansion for sampling a correlation matrix: an efficient GPX-RPMH algorithm. Journal of Statistical Computation and Simulation 2008; 78(11):1065-1076. Accessed by http://www.tandfonline.com/doi/abs/10.1080/00949650701519635#preview.
  23. NasserS, Lai Z, O'Connor S, Xuefeng Liu, Flack J. Does earlier attainment of blood pressure goal translate into fewer cardiovascular events? Current Hypertension Reports 2008; 10(6): 398-404.
  24. Xuefeng Liu, Roth J. Development and validation of an infant morbidity index using latent variable models. Statistics in Medicine 2008; 27(7): 971-989. Accessed by http://www.ncbi.nlm.nih.gov/pubmed/17573677.
  25. Jin B, Tao Q, Peng J, Soo HM, Wu W, Ying J, Fields CR, Delmas AL, Xuefeng Liu, Qiu J, Robertson KD. DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis, and immune function. Human Molecular Genetics 2008; 17(5): 690-709.
  26. Xuefeng Liu, Roth J. A class of latent variable models with an application to development of an infant morbidity index. Proceedings of the American Statistical Association 2007:S458-66.
  27. Flack JM, Duncan K, Ohmit SE, Quah R, Xuefeng Liu, Ramappa P, Norris S, Hedquist L, Dudley A, Nasser SA. Influence of albuminuria and glomerular filtration rate on blood pressure response to antihypertensive drug therapy. Vascular Health and Risk Management 2007; 3(6):1029-3
  28. Xuefeng Liu, Daniels M. A new efficient algorithm for sampling a correlation matrix based on parameter expansion and re-parameterization. Journal of Computational and Graphical Statistics 2006; 15(4):897-914. Accessed by http://www.tandfonline.com/doi/abs/10.1198/106186006X160681#preview.

 

Selected Presentations

  1. Ikekwere JC, Longcoy J, Xuefeng Liu. Diabetes mellitus and uncontrolled blood pressure: The aspect of racial disparity in diagnosed hypertensive patients. Poster presentation, 141th APHA Annual Meeting (November, 2013). Boston, MA (Received Student Research Award at APHA 2013, Congrats! my students).
  2. Cao Y, Xuefeng Liu. Prevalence and associates of vitamin D deficiency and insufficiency among adults in the United States. Poster presentation, Appalachian Student Research Forum (April 4, 2013). Johnson City, TN.
  3. Martin BC, Khoury A, Xuefeng Liu. Using tele-health to affect cardiovascular outcomes in rural areas: The case of southern Appalachia - final results. Oral presentation, 141th APHA Annual Meeting (November, 2013). Boston, MA.
  4. Xuefeng Liu. Approaches to Improving the Health in the US and China. Expert presentation (June 19, 2012), Qingdao Agricultural University, Qingdao, China.
  5. Callahan K, Zheng S, Xuefeng Liu. A cross-sectional analysis of factors associated with violation of Maine's legislation prohibition of smoking in a vehicle with children. Oral presentation, Appalachian Student Research Forum (April 5, 2012). Johnson City, TN.
  6. He Y, Xuefeng Liu. Association between 25-hydroxyvitamin D levels and systolic blood pressure in the middle and elderly adults: results from the national health and nutrition examination survey 2001-2006. Poster presentation, Appalachian Student Research Forum (April 5, 2012). Johnson City, TN.
  7. Cao Y, Khoury A, Xuefeng Liu. Associations of Vitamin D with Prostate Specific Antigen (PSA) Outcomes among Men Aged 40 Years or older in the United States. Poster presentation, Appalachian Student Research Forum (April 5, 2012). Johnson City, TN.
  8. Xuefeng Liu, Wang K, Tsilimingras D. Vitamin D deficiency, insufficiency and pulse pressure. Oral presentation, 140th APHA Annual Meeting (November, 2012). San Francisco, CA.
  9. Xuefeng Liu. Generalized latent trait models for multiple correlated health endpoints. Oral presentation, 140th APHA Annual Meeting (November, 2012). San Francisco, CA.
  10. Cober K, Martin BC, Khoury A, Xuefeng Liu, Clark S. Using tele-health to affect cardiovascular outcomes in rural areas: The case of Southern Appalachia - Preliminary findings. Oral presentation, 140th APHA Annual Meeting (November, 2012). San Francisco, CA.
  11. Xuefeng Liu. Global Health: Approaches to Improving the Quality of Life in the US and China. Expert presentation, China-Tennessee Health Education Training Forum (November, 2011). Johnson City, TN.
  12. Holt T, Liu M, Xuefeng Liu. Racial disparity in albuminuria and its association with hypertension prevalence. Abstract and poster presentation, 139th APHA Annual Meeting (October 29 - November 2, 2011). Washington DC.
  13. Xuefeng Liu. Topic 1: Extended latent variable models with the application to an infant morbidity study; Topic2: Vitamin D deficiency and risk of wide pulse pressure. Invited talk, Department of Biostatistics, Virginia Commonwealth University (June, 2011). Richmond, VA.
  14. Wang K, Xuefeng Liu, Pan Y, Aragam N, Zeng M. FSTL4 and SEMA5A are associated with alcohol dependence: Meta-analysis of two genome-wide association studies. Abstract, 139th APHA Annual Meeting (October 29 - November 2, 2011). Washington DC.
  15. Liu M, Xuefeng Liu. Racial Disparities in Cardiovascular Factors among Diagnosed Hypertensive Patients. Poster presentation, Appalachian Student Research Forum (March 23-24, 2011). Johnson City, Tennessee.
  16. Xuefeng Liu and Kesheng Wang. Impact of Clinic Decision on the Rapidity of Blood Pressure Control. Abstract, 138th APHA Annual Meeting. November 6-10, 2010. Denver, CO.
  17. Wang K, Xuefeng Liu, Aragam N. A Genome-wide Meta-analysis Identifies Novel Loci Associated with Schizophrenia and Bipolar disorder. Poster Presentation, ASHG Annual Meeting. November 2-6, 2010. Washington DC.
  18. Quinn M, Slawson D, Xuefeng Liu, Pack R. Risky Sexual Behaviors and Depressive Symptomatology: A Survey of Tennessee High School Students. Poster Session, TPHA Annual Educational Conference. September 15-17, 2010. Nashville, TN.
  19. Xuefeng Liu. A Class of Latent Trait Models with a Skewed Distribution of Latent Trait. Invited Presentation, SRCOS. June 6-9, 2010. Virginia Beach, VA.
  20. Xuefeng Liu, Meng Liu, Kesheng Wang, and Jeffray Roth. Latent variable models for development of composite indices. Oral presentation, ENAR. March 21-24, 2010. New Orlean, LA.
  21. Egenti U, Xuefeng Liu. Weight Gain and Risk of Visual impairment among US Adults-Results from NHANES 2001-2006. Poster session, ARVO 2010 Annual Meeting. May 2-6, 2010. Fort Lauderdale, FL.


Research Projects

  • Racial Disparities in Screening and Treatment of Hypertension and Diabetes. AHA.
  • Southern Appalachian Tele-Homecare Program. HRSA.
  • Child temperament, Parenting Style, and Childhood Obesity Risk. NIH.
  • Impact of Clinic Decision on the Rapidity of Blood Pressure Goal Attainment.  RDC Major Research Grant.
  • Coordinated School Health Evaluation Program. Tennessee Dept. of Education.
Personal Interests

Music, Basketball, Jogging, Family fun