The National Institutes of Health (NIH) announces the
publication of the revised NIH Grants Policy Statement (NIHGPS, rev.
10/1/2010). This revision is applicable to all NIH grants and
cooperative agreements with budget periods beginning on or after October
1, 2010. This revision supersedes, in its entirety, the NIH Grants
Policy Statement (12/03) as a standard term and condition of award.
However, the December 2003 NIHGPS continues to be the standard term and
condition for all NIH grants and cooperative agreements with budget
periods that began between December 1, 2003 and September 30, 2010.
The NIHGPS provides both up-to-date policy
guidance that serves as NIH standard terms and conditions of awards for
grants and cooperative agreements, and extensive guidance to individuals
that are interested in pursuing NIH grants.
This revision incorporates NIH policy
changes since the December 2003 version, policy clarifications, public
policy changes, terminology changes, new chapters, chapter revisions,
reorganization of the document, as well as other document enhancements
such as a new chapter numbering schema. Some sections have been
rewritten to provide clarity; however, the overall policies in these
sections have not changed. The document is available in the following
electronic formats: HTML and PDF
The link to the 12/03 NIHGPS and all previous versions
will remain the same.
NIH will continue to publish interim
grants policy changes through the issuance of NIH Guide Notices found at
http://grants.nih.gov/grants/guide/index.html. Each change
will be described, including its applicability and effective date; and
the necessary language to implement it as a term or condition of award
A document is available that summarizes
significant changes that are implemented with the October 1, 2010 NIHGPS
(MS Word - 252 KB).
more information, please see the notice at
- NIH's plans for funding noncompeting
research grants under the current continuing resolution
Noncompeting Grant Awards Under the Continuing Resolution
Posted by Jeremy Berg on Monday, Nov 9, 2009 1:37 PM EST
On October 30, the President signed Public Law 111-88, which
includes appropriations for NIH to operate at Fiscal Year 2009
levels through December 18, 2009.
During this period, NIH will make noncompeting research grant awards
at reduced levels, typically up to 90% of the previously committed
level. This approach is consistent with our practice in previous
The policy affects research grants. Research training grants and
fellowship awards will not be affected.
NIH anticipates that noncompeting awards will be adjusted upward
once the level of the final appropriation has been established.
- Important Changes to the NIH
Application Process, effective Jan. 25, 2010
For the latest and most up-to-date info, see the
Due to changes
resulting from the Enhancing Peer Review initiative,
applications for due dates on or after January 25, 2010 require:
Restructured application forms
New instructions including shorter page
affect ALL applications (new, renewal, resubmission, and
Applicants who are eligible for continuous submission may
continue to use current forms and instructions through February
7, 2010 for R01, R21, and R34
AIDS applications that would otherwise have been due on
January 7, 2010.
In December, you will need to download the new
application forms (applies to both electronic SF 424 (R&R) and
paper PHS 398). When the time comes, be sure to choose the
correct application package:
SF 424 (R&R): ADOBE_FORMS_B
PHS 398: Revision date “June 2009”
Steps for Success:
Read about requirement
changes now to be able to begin writing the Research
Strategy section of the application.
In December, go back
to the updated FOA or reissued Parent Announcement and download
the new application package and instructions.
Read the new application
For due dates on or
after January 25, submit applications using the new
application forms and instructions.
How to Get Informed!
To better understand
the new requirements, the
Enhancing Peer Review Website has a page dedicated to
application changes and has made available to you a number
of resources on the
Training and Communications Resources page including:
one page update
PowerPoint presentations describing the changes
Additional information is also available
throughout the website including:
A video overview of
the changes will be available on the Enhancing Peer Review Web
Training and Communication Resources in mid-November.
The Enhancing Peer
Review website will continue to be updated with additional
resources as they are developed. To be notified when new
application packages become available, sign up on the Enhancing
LISTSERV or look out for an announcement in the
NIH Guide for Grants and Contracts.
- NIH announces a change in the existing
policy on resubmission (amended) applications
"Beginning with applications intended for the January 25, 2009
due date, all original new applications (i.e., never submitted) and
competing renewal applications will be permitted only a single
amendment (A1). For this and subsequent cohorts of original new and
competing renewal applications, any second amendment (A2) will be
administratively withdrawn and not accepted for review. Applicants
who fail to receive funding after two submissions may resubmit but
only if the application is fundamentally revised to qualify as new.
A new application is expected to be substantially different in
content and scope with more significant differences than are
normally encountered in an amended application. Note that there is
no time limit for the submission of the original and subsequent A1
Original new and competing renewal applications that were
submitted prior to January 25, 2009 will be permitted two amendments
(A1 and A2). For these “grandfathered” applications, NIH expects
that any A2 will be submitted no later than January 7, 2011, and NIH
will not accept A2 applications after that date.
This policy applies to all applications, including applications
submitted under the NIH Small Business Innovation Research (SBIR)
and Small Business Technology Transfer (STTR) programs, Career
Development Awards, Individual Fellowships, Institutional Training
Grants, Resource Grants, Program Projects, and Centers. Currently no
amendments are permitted for applications received in response to a
Request for Applications (RFA) unless it is specified in the Funding
Opportunity Announcement, in which case only one amendment will be
For the background and full text announcement of this notice,
- NIH Announces Changes to Enhance
Peer Review (posted June 9, 2008)
National Institutes of Health (NIH) Director Elias A. Zerhouni,
M.D., announced on June 6th
at the 96th Meeting of the Advisory Committee to the
Director (ACD) critical changes to enhance and improve the NIH peer
View the related press
More details on these changes are described in a .PDF
document distributed at the meeting. You may view this file at
More information on the Enhancing NIH Peer Review initiative is
- Policy requires scientists to
submit final, peer-reviewed manuscripts that arise from NIH funds to PubMed Central
Public Access Policy ensures that the public has access to
the published results of NIH funded research. It requires scientists
to submit final, peer-reviewed manuscripts that arise from NIH funds to the digital archive PubMed Central (http://www.pubmedcentral.nih.gov/).
The Policy requires that these articles be accessible to the public
on PubMed Central to help advance science and improve human health.
- The NIH Public Access Policy applies to all peer-reviewed
articles that arise, in whole or in part, from direct costs
1 funded by NIH, or from NIH staff,
that are accepted for publication on or after April 7, 2008.
- Institutions and investigators are responsible for ensuring
that any publishing or copyright agreements concerning submitted
articles fully comply with this Policy.
- PubMed Central (PMC) is the NIH digital
archive of full-text, peer-reviewed journal articles. Its
content is publicly accessible and integrated with other
- The final, peer-reviewed manuscript includes all graphics
and supplemental materials that are associated with the
- Beginning May 25, 2008, anyone submitting an application,
proposal or progress report to the NIH must include the PMC or
NIH Manuscript Submission reference number when citing
applicable articles that arise from their NIH funded research.
This policy includes applications submitted to the NIH for the
May 25, 2008 due date and subsequent due dates.
What Investigators Should Do
- Make sure that any copyright transfer or other publication
agreements allow the final peer-reviewed manuscripts to be
submitted to NIH in accordance with the Policy.
Some publishers make the final published version of every NIH-funded
article publicly available in PubMed Central within 12 months of
publication, without author involvement. See
a list of these journals.
For any journal other than one of those in this list, the
- Inform the journal that the final peer-reviewed
manuscript is subject to the Public Access Policy when
submitting it for publication.
- Make sure that any copyright transfer or other
publication agreement allows the final peer-reviewed
manuscript to be submitted to NIH in accordance with the
Policy. For more information, see the FAQ
approval do I need to submit my article to PubMed Central?
and consult with your Institution.
- Submit the final peer-reviewed manuscript to NIH, upon
acceptance for publication. See the
Submission Process for more information.
- When citing their NIH-funded papers in NIH applications,
proposals or progress reports, authors must include the PubMed
Central reference number for each article.
For more information on these processes, see
- As of April 7, 2008, all final peer-reviewed manuscripts
arising from NIH funds must be submitted to PubMed Central upon
acceptance for publication.
- As of May 25, 2008, NIH applications, proposals, and
progress reports must include the PubMed Central reference
number when citing a paper that falls under the policy and is
authored or co-authored by the investigator, or arose from the
investigator’s NIH award. This policy includes applications
submitted to the NIH for the May 25, 2008 due date and
subsequent due dates.
applicants are trying to get around the eRA Commons registration
requirements by “borrowing” a PI Commons ID from a colleague. This
sleight of type may help you pass the system checks, but NIH has
equally clever staff in Receipt and Referral that will catch you at
the next check point (you know, the point where real people are
looking at the application and making decisions). Using the Commons
ID of a different individual will result in that individual being
listed as the PD/PI for the grant application in the NIH data system
and that individual will have access to the review outcome and
summary statement. A PI’s Commons ID should be regarded as their
NIH PIN number – it belongs to the Principal Investigator only!
By submitting an
application you are certifying that the contents are true, complete
and accurate. Please plan ahead and get the necessary accounts in
place prior to submission.
Unique Applications Deserve Unique Names
Did you know that
a “New” application must have a different title from any other
application with the same PD/PI? NIH has had several cases reported
to the help desk where PD/PIs have tried to reuse the title provided
in the “Descriptive Title of Applicant’s Project” field (field #11
of the SF424 (R&R) form). Before you call foul, they did
significantly change the specific aims of the project. The eRA
Commons system did just what it was supposed to do – it replaced the
first application submitted with the second. Application titles must
be unique…it says so in the Application Guide so it must be true!
- The NIDA Plans to Reissue an RFA for the
Genes, Environment, and Development Initiative (GEDI), supporting
research investigating the etiology of drug abuse.
(posted Sept. 10, 2007)
The reissue will be in the fall of 2007, with review and funding
expected by the end of fiscal 2008 (September 2008), to augment the
Genes, Environment, and Development Initiative (GEDI). This
initiative will support research investigating interactions among
genetic, environmental, and developmental factors in the etiology of
Prior lines of research have established that genetic,
environmental, and developmental factors all contribute to
vulnerability to drug experimentation, use, and progression to abuse
and dependence and to the transitions among these stages. Numerous
high quality longitudinal and developmental datasets are currently
available which provide a wealth of individual-level, familial, and
other environmental data on individuals who are at risk for, or are
in the course of development, progression, and desistance of, drug
abuse. Studies qualifying for submission under this Request for
Applications will be longitudinal in design; cover at least two
developmental periods; assess subjects in or through the period of
risk for drug abuse; have rich environmental data; include
categorical and quantitative measures of both drug abuse and
relevant psychiatric or behavioral phenotypes; and will have the
ability to collect and share DNA, and to join the NIDA
Proposals are expected to demonstrate sufficient power to study
main effects and interactions, and to include plans and datasets for
replication. Where data are pooled across studies or used for
replication, reasonable comparability will need to be shown. The
investigative teams are expected to be interdisciplinary, with the
appropriate expertise to address these complex interactions. Funded
research is expected to yield a richer understanding of the true
contributions of and interactions among individual, environmental
and transitional factors in the etiology of drug abuse and,
ultimately, lead to improved preventive and treatment interventions
for these complex and costly disorders. The previously released RFA
can be found at
and includes a link to frequently-asked questions with further
This notice was officially published at
- Research on Interventions for
Child Abuse and Neglect (R01)
(posted August 22, 2007)
NIH is soliciting research project grant (R01) applications
focused on conducting efficacy and effectiveness trials of child
abuse and neglect interventions at various levels. Given the
public health need for children and families who experience the
negative effects of child abuse and neglect, interventions in which
preliminary developmental/exploratory work has already been
undertaken, and pilot studies, or in some cases efficacy trials,
have demonstrated positive change are strongly encouraged.
(For those interventions that need preliminary research, applicants
should consider additional mechanisms, which are used to establish
efficacy, including the R21 and R34, as appropriate.)
Of particular interest is the development of large scale trials
designed to target either or both the victims or perpetrators of
child abuse and neglect, including preventive interventions. Child
abuse and neglect is a complex public health issue likely caused by
a myriad of factors, including individual-, family-, and
community-level elements. Thus, a research program focused on
understanding and addressing these problems must necessarily draw
upon interdisciplinary theories and approaches.
One of the goals is to bring together multi-disciplinary and
translational perspectives encompassing basic biomedical, behavioral
and social science research in mental health, physical health,
public health and prevention, alcohol and substance abuse,
neurology, injury, trauma and child development, to advance our
knowledge of child abuse and neglect. Only projects proposing
rigorous scientific research designs will be considered; service
demonstrations or other types of service programs are not eligible
for funding under this program.
Application Deadline: February 5, 2008
Earliest Date an application may be submitted: December 7,
For the full announcement, see:
Grants.gov Extends Transition Time for Agencies
(June 29, 2007)
originally targeting the end of FY2007 to have all agencies
transitioned to the new Adobe-based forms, Grants.gov has extended
the time provided to agencies to fully transition to the new format
into 2008. This is great news for both agencies and applicants. The
additional time allows Grants.gov to complete their development and
testing of the new forms and provides agencies with greater
flexibility in how they approach the transition. Our shared goal is
the smoothest transition possible for our applicants.
to the Adobe forms remains on hold while we wait for Grants.gov to
finalize the SF424 (R&R) form set. NIH does not expect to be
positioned to post new application packages with the Adobe-based
forms this summer. So, just keep using the current Grants.gov forms
until we hear otherwise from NIH. They’ll continue to keep us posted
on their progress through their electronic submission listservs.
Once the transition plans are finalized, formal announcements also
will be posted in the
NIH Guide for Grants and Contracts and in the
NIH Extramural Nexus.
eSubmission Application Viewing Window &
reevaluated its policy of including Federal holidays in the two
weekday window provided to applicants to view their assembled
application prior to it moving forward for review and funding
consideration. Effective immediately (thus including July 4, 2007),
Federal holidays will be excluded from the two weekday
application viewing window. See
NIH/AHRQ/NIOSH Announce Change in Electronic Submission Process –
Federal Holidays Excluded from Application Viewing Window for
- The May 2007 NIH Public
Bulletin is online (May 11, 2007)
Read about the latest public events, activities, and health
information resources from the National Institutes of Health (NIH)
in the May 2007 issue of the NIH Public Bulletin. Here’s your
- Find out what happened at the spring meeting of the NIH
Director’s Council of Public Representatives.
- Learn about the newly appointed NCRR and NIDDK Directors.
- Participate in a teleconference about cancer clinical
- Read the summary of a research workshop on children with
- Discover a new lecture series on the frontiers of
- Find out how you can join in Healthy Vision Month and other
activities in May.
- Take an online diabetes risk test.
- Check out a new monthly podcast series on women’s health
View the latest issue of the NIH Public Bulletin at:
For prior issues, visit
http://getinvolved.nih.gov and click on "All Issues".
- NIH: Delegation of PI Status
Access to Assistant for Electronic Application Review (May
PIs can now delegate the ability to view the status of
electronically submitted applications to any commons-registered
individual with an ASST role. This new menu choice is found in
Admin menu by selecting Account/Delegate Status. Once in the
Delegate Status screen, users will see a list of all individuals
registered with the ASST role and can “Delegate” and “Remove”
delegation for those individuals. For detailed instructions on
how to delegate this authority see
eRA Commons Release Notes Version 126.96.36.199.
Once this delegation has been granted, the ASST will be able
to view and access the list of applications associated with the
PI. Individuals can have this authority delegated to them by
more than one PI. The view these delegated individuals will have
is equivalent to that of a signing official (SO View) and does
not include access to confidential information; e.g., summary
statements and priority scores.
To anyone that shared their account login information (you
know who you are), please use the delegate authority option and
change your passwords immediately. Good security practices
- NIH Announces Changes
to eRA Commons (May 11, 2007)
NIH Announces Changes to eRA Commons, Particularly the
Electronic Streamlined Non-competing Award Process (eSNAP)
NOT-OD-07-064). The notice covers
changes to institutional profile assurances/certifications,
changes to eSNAP functionality and other Commons updates.
You can find out about assurances and certifications in
Part III: Policies, Assurances, Definitions of the
NIH Grants.gov Application Guide SF424 (R&R).
- NIH: Issue and Resolution
with NoA letter (May 11, 2007)
Due to a problem with eNotifications after the deployment of
the new Notice of Award (NoA), about 500 NoA emails were not
sent to grantees during the week of April 16th. The grantee
eNotification problem was fixed and all of the missing NoA
eNotifications from the week of April 16th were sent out on
May 9th. NIH is also aware of a problem with the NoAs not
appearing in the correct format in eRA Commons, and is
working on a resolution and hopes to correct the problem
For more information about the new NoA, please
refer to the NIH Guide for Grants and Contracts, Notice
Questions regarding this NoA issue
should be directed to the eRA Commons Help Desk:
method of contact)
Hours: Mon-Fri, 7 a.m. to 8 p.m. Eastern Time
Back to the
- New NSF Proposal & Award Policies & Procedures Guide
(May 1, 2007)
The National Science Foundation has recently published a new NSF
Proposal & Award Policies & Procedures Guide (NSF 07-140).
This document comprises two previously standalone NSF policy
documents, the NSF Grant Proposal Guide (GPG) and the Grant Policy Manual (GPM),
combining them into a single
electronic policy framework. The new NSF Proposal & Award
Policies and Procedures Guide (NSF 07-140) will be effective for
proposals submitted on or after June 1, 2007. This document
supersedes all prior versions of the GPG and GPM and can be accessed
- National Institutes of Health (NIH) announces the revision of
the NoA lettter
(May 1, 2007)
The Notice of Grant Award Letter, now known as the Notice of
Award Letter (NoA), has been revised to include several enhancements
and a new look and feel. This revised NoA gives NIH the flexibility
to make changes as needed and issue the NoA in PDF format resulting
in a more user / reader friendly document. NIH will start to issue
the revised NoA effective April 13, 2007. For detailed information
about the enhancements and other information, please see
- NIH Announces Delay in Transition of K, F, T and
Complex Grant Programs (May 1, 2007)
NIH has announced that they have delayed the timeline for
transition to electronic submission for the following
mechanisms: K, F, T, D and complex mechanisms (P & U).
These mechanisms were previously scheduled to transition no
later than October 2007. NIH has not specified a new
timeline, but has indicated that it will be issued as soon
Please note that the mechanisms that are scheduled to
transition to electronic submission this May (G7, G8, G11,
G13, G20, S11, S21, and S22) will still transition. All
applications in response to announcements for these programs
must be submitted electronically through
For full information, please