Besides undergraduate general core classes, the Bristol campus offers upper level classes in several majors, and graduate classes as well. In addition, the campus often groups courses towards an undergraduate or a graduate major and offers them at a similar time each semester, allowing students to complete a major over several semesters. Sometimes these are operated as "Cohorts".

Some cohorts in progress include the undergraduate Criminal Justice cohort, offered Mondays at 4:00 p.m. and 7:00 p.m. each semester; the MBA cohort, with classes offered at 4:00 p.m. or 7:00 p.m. selected Mondays through Thursdays; and the Early Childhood Education Graduate cohort, offered at 4:30 on Wednesdays, and the undergraduate business management courses offered at varying times.

COHORTS
Cohorts are groups of students progressing through a major together providing mutual support to each other.
New graduate cohorts being formed for fall 2005 include the following:

• MATHEMATICS (M.A.) -- The Department of Mathematical Sciences offers a program of study leading to the Master of Science (M.S.) degree with a concentration in Precollegiate Mathematics. The precollegiate mathematics concentration is designed for in-service teachers and consists of an eight-hour sequence with two tracks - a K-8 mathematics track and a 7-12 track - with the aim of producing an in-depth , profound understanding of the mathematics taught in elementary, middle, and high school. In addition, there are six hours of independent study and thesis research.
• READING (M.A.) -- East Tennessee State University offers a Cohort program for the Master of Arts in Reading Education with a format that also qualifies participants for endorsement as Tennessee PreK-12 Reading Specialists. The program is to be completed in 18 months.  For information, contact Dr. E. Jane Melendez at (423) 439-7910, email: melendez@etsu.edu.
• COUNSELING (Ed.S.) -- East Tennessee State University offers a new part-time cohort program for the Education Specialist degree in Educational Leadership with a concentration in School Counseling One night a week – ETSU at Bristol. For information, contact Dr. Patricia E. Robertson at (423) 439-7693, email: robertpe@etsu.edu.
• Physical Education (M.A.) --  K-12 and add on endorsement. For information, contact Dr. Diane Mozen at (423) 439-7981, email: mozend@etsu.edu
• Media/Technology (M.A.) –- for educators and librarian (media specialists). For information, contact Lee Daniels at (423) 439-4262 email: danielsh@etsu.edu
• English as a Second Language (ESL) –- add on certificate for teachers. For information, contact Rhona Cummings at (423) 439-7598 email: cummingr@etsu.edu