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College of Arts & Sciences

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Abbas  Shilabin 

Assistant Professor
423-439-6917 /
Brown Hall Room 401


  • Drug/Inhibitor Design and Discovery
  • Synthetic/Medicinal Chemistry of Biologically Active Compounds
  • Natural Products Chemistry


  • Osazee, J. O.; Annor-Gymafi, J. K.; Slebodnick, C.; Shilabin, A. G., Structure-Based Discovery and Synthesis of Pyrrolo[2,1-c][1,4]-benzodiazepine Derivatives as Non-β-lactam Serine β-lactamase Inhibitors. Int. J. Drug Dev. & Res. 2016, 8, 24-33.
  • Ahern J. C.; Shilabin A. G.; Henline, K. M.; Pike, R. D.; Patterson, H. H. Photophysical properties of {[Ag(CN)2]-}2 complexes trapped in a supramolecular electron-acceptor organic framework. Dalton Trans. 2014, 43, 12044-12049.
  • Shilabin, A. G.; Dzhekieva, L.; Misra, P; Jayaram B.; Pratt, R. F. 4-Quinolones as Noncovalent Inhibitors of High Molecular Mass Penicillin-Binding Proteins. ACS Med. Chem. Lett. 2012, 3, 592-595.
  • Chen, L.: Lei, Y.; Shilabin, A. G., Baran, G. R.; Sieburth, S. M. β-Peptide Coatings by Surface-Initiated Polymerization. Chem. Commun. 2012, 48, 9604-9606.
  • Shilabin, A. G.; Hamann, M. T. Synthesis and Evaluation of Kahalalide F Analogs with Improved Antitumoral and Antimicrobial Activities. Bioorg. Med. Chem. 2011, 19, 6628-6632.
  • Gao, J.; Caballero-George, C., Wang, B.; Rao, K. V.; Shilabin, A. G.; Hamann, M. T. 5-OHKF and NorKA, Depsipeptides from a Hawaiian Collection of Bryopsis pennata: Binding Properties for NorKA to the Human Neuropeptide Y Y1 Receptor. J. Nat. Prod. 2009, 79, 2172-2176.
  • Shilabin, A. G.; Kasanah, N.; Tekwani, B. L.; Hamann, M. T. Kinetic Studies and Bioactivity of Potential Manzamine Prodrugs. J. Nat. Prod. 2008, 71, 1218-1221.
  • Ibrahim, M. A.; Shilabin, A. G.; Prasanna, S.; Jacob, M.; Khan, S. I.; Doerksen, R. J.; Hamann, M. T. 2-N-Methyl Modifications and SAR Studies of Manzamine A. Bioorg. Med. Chem. 2008, 16, 6702-6706.
  • Schmidt, A.; Lindner A. S.; Shilabin, A. G.; Nieger, M. New Derivatives and Ring Systems of Annulated Pyrrolobenzo[1,4]diazepins. Tetrahedron 2008, 64, 2048-2056.
  • Shilabin, A. G.; Kasanah, N.; Wedge, D. E.; Hamann, M.T. The Lysosome and HER3 (ErbB3) Selective Anticancer Agent Kahalalide F: Semisynthetic Modifications and Structure-Activity Relationship Studies. J. Med. Chem. 2007, 50, 4340-4350.
  • Schmidt,  A.; Shilabin, A. G.; Namyslo, J. C.; Nieger, M.; Hemmen, S. Pyrimidine-annulated Pyrrolobenzodiazepines. A New Ring System Related to Aspergillus Alkaloids. Eur. J. Org. Chem. 2005, 1781-1789.
  • Schmidt, A.; Shilabin, A. G.; Nieger, M. Syntheses and Tautomerisations of Amino-Substituted and Pyrimidine-Annulated Pyrrolobenzodiazepines. Heterocycles 2005, 65, 625-632.
  • Schmidt, A.; Shilabin, A. G. Thia-diazabenzo[g]cyclopenta[e]azulene-diones. Syntheses and Properties of a New Ring System. Heterocycles 2004, 63, 2851-2858.
  • Schmidt, A.; Shilabin, A. G.; Nieger, M. On Benzo[b][1.4]diazepinium-olates, -thiolates and -carboxylates as Anti-Hückel Mesomeric Betaines. Org. Biomol. Chem. 2003, 1, 4342-4350.
  • Schmidt, A.; Shilabin, A. G.; Nieger, M. Synthesis and X-ray Structure of 2,4-Dimethyl-6,7-benzo[1,5]diazepinium Picrates. Heterocycles 2003, 60, 2645-2651.
  • Shilabin, A. G.; Entezami, A. A. Electrochemical Behavior of Conducting Polyfuran Derivatives Containing Pyrrole, Thiophene and Ethylenic Spacers. Eur. Poly. J. 2000, 36, 2005-2020.
  • Shilabin, A. G.; Entezami, A. A. A review on conducting polyfurans synthesis, properties and their applications. J. Sci. Tech. Poly. 1997, 10, 355-374.


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