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Center of Excellence for Inflammation, Infectious Disease & Immunity

Quillen College of Medicine

Center News

Two Faculty Members Co-Author Textbook Chapter

East Tennessee State University faculty members Dr. Kesheng Wang and Dr. Liang Wang have contributed a book chapter to the textbook, Molecular Aspects of Alcohol and Nutrition.

The book was edited by Dr. Vinood Patel of the University of Westminster in London, and was published by Academic Press in November. 

Drs. Wang and Wang, who both work in the Department of Biostatistics and Epidemiology within ETSUs College of Public Health, co-authored the chapter titled Genes Associated with Alcohol Withdrawal.

Worldwide, alcohol is the third leading risk factor for disease burden associated with 2.5 million deaths every year.

Alcohol dependence is a complex disease, with devastating effects on individuals, families and society, Kesheng Wang said.

It is estimated that 76.3 million people worldwide have suffered from alcohol use disorders, including alcohol abuse and alcohol dependence.

Alcohol withdrawal refers to a cluster of symptoms that may occur when a heavy drinker suddenly stops or significantly reduces his or her alcohol intake. These symptoms can start as early as two hours after the last drink, persist for weeks, and range from mild anxiety and shakiness to severe complications, such as seizures and delirium tremens.

Family, twin and adoption studies have indicated that genetic and environmental factors contribute to the development of alcohol dependence, Liang Wang said.

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Several gene-related studies have successfully identified chromosome regions and genes related to alcohol dependence and alcohol withdrawal symptoms. The chapter reviews the recent findings in genetic studies of alcohol withdrawal symptoms.

Molecular Aspects of Alcohol and Nutrition is a resource for nutrition researchers and nutritionists who study or treat alcohol-related diseases. Experts from across the field of alcohol research explain how alcohol disrupts normal fat, carbohydrate and protein metabolic processes in the liver and other parts of the body.

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