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In-Vivo Xtreme Core Facility

Quillen College of Medicine

In-Vivo Xtreme Equipment

In-Vivo Xtreme Optical Imaging System
By Bruker


Designed for imaging of luminescent and  fluorescent probes within small animals, and X-ray imaging of small animals.


Technical Details

Camera and Lens

Detector Type:  Back-thinned, back-illuminated (BI) 4MP CCD detector

CCD Pixel:   BI 4MP: 2048 x 2048

CCD Size:   BI 4MP: 27.6 x 27.6 mm Size of Pixel on Sensor 

Size of Pixel on Sensor     BI 4MP: 13.5 m

Read Noise       BI 4MP: 3 e-

FOV     BI 4MP: 7.2 x 7.2 cm to 20 x 20 cm

Lens:   f/1.1 f/16, 58 mm lens, fixed

Luminescence Sensitivity     BI 4MP:   <50 photons/sec/cm2/sr

Fluorescence Specifications

Light Source: 400WXenon illuminator

Excitation Filters: 28

Excitation Wavelength Range: 410 nm 760 nm

Emission Filters: 6 filters, 8 position wheel

Emission Filter Wavelength Range: 535 nm 830 nm

Patented High-Sensitivity Wide Angle Filters: Yes

X-ray Specifications

Maximum Resolution (lp/mm):  BI 4MP: > 18 lp/mm

X-ray Spot Size (Nominal m): <60 m

Energy Range (kVp): 20-45 kVp

Max Current (A): 500 A

Filters:0.1 mm, 0.2 mm, 0.4 mm, 0.8 mm, or no filter

Physical Specifications

Footprint (W x D x H cm): 72 x 84 x 183 cm

Imaging Modalities: Fluorescence, luminescence, radioisotopic, and radiographic

Catheter Ports: Yes

Compatible with most commercial gas anesthesia: Yes

Animal Warming: Warm air 20C 40C

Computer Supplied: Yes





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