As the leader of the multi-disciplinary Sub-Cellular Pharmaceutics Laboratory (SCPL),
Zac is interested in a variety of drug-targeting strategies. One of the main efforts
of the lab is designing organelle-specific drug delivery systems for therapeutic macromolecules.
Research conducted in the lab is supported by the RDC, ETSU Honors College, and AACP.
Education, Degree, & Post Graduate Training:
Post-Doctoral Researcher, University of Michigan, 2008-2011
Walls ZF, Gong H, Wilson RJ. “Liposomal Coencapsulation of Doxorubicin with Listeriolysin
O Increases Potency via Subcellular Targeting.” Mol Pharm. 13(3):1185-90, 2016.
Walls ZF, Gupta SV, Amidon GL, Lee KD. “Synthesis and Characterization of Valyloxy
Methoxy Luciferin for the Detection of Valacyclovirase and Peptide Transporter.” Bioorg
Med Chem Lett. 24(20):4781-3. 2014.
Walls ZF, Goodell S, Andrews CD, Mathis J, Lee KD. "Mutants of Listeriolysin O for
Enhanced Liposomal Delivery of Macromolecules." J Biotechnol. 164(4):500-502, 2013.
Loening AM, Walls ZF. "Engineering Luciferases for Assays and Imaging." Engineering
in Translational Medicine. Ed. Cai W. Springer, 2014.
American Association of Pharmaceutical Scientists (AAPS)
World Molecular Imaging Society (WMIS)
American Association of Colleges of Pharmacy (AACP)