Predicting Drug Withdrawal Using Cord Blood
Infants who are exposed in utero to drugs used to treat opioid addiction, namely buprenorphine, often endure drug withdrawal upon delivery. This condition, Neonatal Abstinence Syndrome (NAS), is often unpredictable as to which exposed children will enter withdrawal. Dr. Stacy Brown’s research group has developed a novel method for measuring buprenorphine metabolites in a baby’s umbilical cord blood using a technique called liquid chromatographymass spectrometry (LC-MS). These metabolites are being investigated as tools to help predict which infants will show NAS. Above is a photo of Haley Trivett Peters (2015) with her work from Dr. Brown’s lab at the ASRF meeting.
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