About Us



The Proteomics and Mass Spectrometry Facility at ETSU was started by Dr. William L. Stone in 2007. We are located in Building 119 (see interactive map ) at the James H. Quillen College of Medicine, East Tennessee State University, in Johnson City, TN 37614. Our facility is dedicated to provide a wide variety of mass spectrometry related services to all interested researchers at the ETSU as well as to outside users. The Center serves as a resource offering analytical and instructional expertise in contemporary mass spectrometric techniques with the primary goal of providing investigators with access to "state-of-the-art" LC/MS instrumentation, expert consultations and "hands-on" training (if needed) to meet their research interests.

 

William L. Stone, Ph.D.       Facility D irector

Dr. Bill Stone is the Director of Pediatric Research and his research focuses on free radical biology and medicine (pediatrics, cancer and cardiovascular disease) with emphasis on nutritional antioxidants as well as proteomics. The Pediatric Research Laboratory has developed state-of-the-art techniques for evaluating oxidative stress and antioxidant status in human subjects and in various model systems.  Dr. Stone received both his B.S. (Chemistry, 1966) and Ph.D. (Molecular and Cellular Biology, 1972) degrees at State University of New York at Stony Brook. Postdoctoral training was completed in the Biochemistry Department at Duke University Medical Center. Dr. Stone's predoctoral and postdoctoral works were in the area of physical chemistry of macromolecules with particular emphasis on hydrophobicity and forces stabilizing lipid-protein complexes (biological membranes and plasma lipoproteins).  Dr. Stone joined the Department of Pediatrics at ETSU in 1989, serves as the Director of Pediatric Research and teaches a graduate level course in Proteomics.

    

  
Marianne Brannon, Ph.D.       Lab Manager

Marianne is a Postdoctoral Researcher and Laboratory Coordinator in the Pediatric Research Group. Marianne has expertise and experience in biochemistry, biosensor technology, cellular biology and microbiology, including teaching experience.  Marianne provides mass spectrometry analysis and datbase searches for the Mass Spectroscopy Facility.  Marianne received her B.S. degree in Agriculture (Food Science) at the University of Florida, Gainesville. She has held her Ph.D. in Biology from University of South Florida, Tampa, since 1996.

Oversight Committee


Dr. Gregory A. Ordway,   Chair, Department of Pharmacology
Quillen College of Medicine, Head of Oversight Committee

Dr. Michelle Duffourc, Director, Molecular Biology Core Facility
Quillen College of  Medicine

Dr. W. Scott Champney,  Chair, Department of Biochemistry and Molecular Biology
College of Arts and Sciences

Dr. Gary L. Wright, Associate Professor, Department of Pharmacology
Quillen College of Medicine