Dr. Peterson collaborates to study improving heart function after a heart attack
Dr. Jonathan Peterson, Assistant Professor in the Department of Health Sciences in
the ETSU College of Public Health, is a member of a team of researchers at East Tennessee
State University studying whether Coenzyme Q10 could help improve heart function after
an individual suffers a heart attack. Dr. Peterson states, "Muscle fatigue is a
common side-effect of statin drug treatment because statins not only reduced cholesterol
they also lower Coenzyme Q10 levels, a key metabolic molecule for cellular energy
production.”While over-the-counter Coenzyme Q10 currently is available for supplementation,
it is fat-soluble, making it difficult to absorb, especially for those who are not
eating fatty foods.
The team will be studying how to increase Coenzyme Q10’s absorption ability by making
it water-soluble. According to Dr. Peterson, “This study will provide a fundamental
insight into the impact of restoring the muscle energy production capacity on the
quality of life and overall health outcomes of patients taking statins.”
One-hundred patients of Dr. Kamesh Sivagnanam, a cardiology fellow at Quillen ETSU
Heart, will take part in the research to determine if the water-soluble Coenzyme Q10
impacts the heart’s ability to function.Dr. W. Andrew Clark, associate dean of research
in ETSU’S College of Clinical and Rehabilitative Health Sciences and professor in
the Department of Allied Health Sciences, is the principal investigator on the project.
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