In 2007, Brooks Pond became one of the inaugural faculty at the Gatton College of
Pharmacy. Brooks received her Ph.D. in Pharmacology from Duke University, where she
worked closely with Rochelle Schwartz-Bloom and George Augustine. After graduation,
Brooks completed a 2 year postdoctoral fellowship in Developmental Neurobiology at
St. Jude Children's Research Hospital under the mentorship of Richard Smeyne. Although
her expertise is in the field of neuropharmacology, she enjoys teaching in many areas
of physiology and pharmacology. Brooks also loves working with both graduate students
and pharmacy students in the laboratory, where she seeks to better understand the
consequences of psychostimulant use on the brain.
Education, Degree, & Post Graduate Training
B.S. in Biochemistry and Molecular Biology (2000) & Minor in Biology from Centre College,
Danville, KY - Graduated Phi Beta Kappa Ph.D. in Pharmacology & Certificate in Cell and Molecular Biology , Duke University,
Durham, NC (2004) Postdoctoral fellowship in Developmental Neurobiology, St. Jude Children's Research
Hospital, Memphis, TN
Phi Beta Kappa (2000- present) Ruth L. Kirschstein National Research Service Award (NRSA) predoctoral fellowship
(2002-2004) American College of Neuropsychopharmacology Young Investigator Award (2006) Graduate research highlighted on the cover of the Society for Neuroscience Annual
Report (2007) Faculty excellence in research award (2009) Faculty excellence in service award (2013) Faculty excellence in teaching award (2015) Outstanding teacher of the year awards (2009, 2010, 2011, 2013) Faculty Hooder (2011, 2013, 2016)
Human Physiology, Non-Medicinal Drug Use, Integrated series courses: Neurology/Psychiatry,
Men's and Women's Health, Nephrology, Critical Care and Toxicology
Our laboratory is interested in long-term effects of psychostimulants. Current projects
include an investigation of long-term effects of methylphenidate on neurogenesis within
the hippocampus and an analysis of the neurochemical effects of the synthetic cathinones
previously legally marketed as "bath salts". In addition, the laboratory is currently
utilizing high pressure liquid chromatography-mass spectrometry (LC-MS) to characterize
the pharmacokinetic profile of some of these compounds.
J. Peters, R. Keasling, S. D. Brown, and B. B. Pond (2016) Quantification of synthetic
cathinones in rat brain using HILIC-ESI-MS/MS. Journal of Analytical Toxicology,
H. T. Peters, L. G. Strange, S. D. Brown, and B. B. Pond (2016) The pharmacokinetic
profile of methylphenidate use in pregnancy: a study in mice. Neurotoxicology and
J. Bentley, F. Snyder, S. D. Brown, R. W. Brown, and B. B. Pond (2015) Sex differences
in the kinetic profiles of d- and l- methylphenidate in the brains of adult rats.
European Review for Medical and Pharmacological Sciences, 19(13):2514-9.
S. A. Allen and B. B. Pond (2014) Chromatographic and electrophoretic strategies for
the chiral separation and quantification of d- and l-threo methylphenidate in biological
matrices. Biomedical Chromatography, 28: 1554-64.
C. C. Combs, E. L. Hankins, C. L. Copeland, S. D. Brown, and B.B. Pond (2013) Quantitative
determination of d- and l- enantiomers of methylphenidate in brain tissue by liquid
chromatography-mass spectrometry. Biomedical Chromatography, 27: 1587–1589.
B.B. Pond, S. Sadasivan, A.K. Pani, C. Qu, Y. Jiao, and R. J. Smeyne. (2012) Methylphenidate
exposure induces dopamine neuron loss and activation of microglia in the basal ganglia
of mice. PLoS ONE. 7(3):e33693.
B. B. Pond, K. Berglund, T. Kuner, G. Feng, G. J. Augustine, and R. D. Schwartz-Bloom.
(2006) The Chloride Transporter Na+-K+-Cl– Cotransporter Isoform-1 Contributes to
Intracellular Chloride Increases after In Vitro Ischemia. Journal of Neuroscience.
Significant Regional, State, or National Service:
ETSU University Committee on Animal Care, ETSU Research Development Committee, GCOP
Curriculum Revision Task Force, GCOP Academic Progression Committee, GCOP Admissions
American Society of Pharmacology and Experimental Therapeutics (ASPET) Society for Neuroscience (SfN)
Personal motto or favorite quote:
"Do all the good you can. By all the means you can. In all the ways you can. In all
the places you can. At all the times you can. To all the people you can. As long as
ever you can." ― John Wesley