Michelle Chandley

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EDUCATION

Postdoctoral Training, 2014, Quillen College of Medicine, East Tennessee State University, Department of Biomedical Sciences

Ph.D., 2008, Quillen College of Medicine, East Tennessee State University, Department of Biomedical Sciences

B.S., 1995, Mars Hill College, Major: Biology

COURSES TAUGHT

Human Anatomy

RESEARCH FOCUS

Neuron and glia pathology of psychiatric disorders including autism spectrum disorder, schizophrenia and major depressive disorder.

SELECTED PUBLICATIONS

Chandley MJ, Szebeni A, Szebeni K, Crawford JD, Stockmeier CA, Turecki G, Kostrzewa RM, and Ordway GA. Elevated gene expression of glutamate receptors in noradrenergic neurons from the locus coeruleus in major depression. The Int J of Neuropsychopharmacol, 1-10. (2014) Epub ahead of print.

Szebeni A, Szebeni K, DiPeri T, Chandley MJ, Crawford JD, Stockmeier CA, & Ordway GA. Shortened telomere length in white matter oligodendrocytes in major depression: potential role of oxidative stress. Int J Neuropsychopharmacol, 1-11. (2014) Epub ahead of print.

Chandley MJ, Szebeni K, Szebeni A, Crawford JD, Stockmeier C, Turecki G, Miguel-Hidalgo JJ, and Ordway GA. Gene expression deficits in pontine locus coeruleus astrocytes in men with major depressive disorder. J Psychiatry Neurosci. July:38(4):276-84. (2013)

Ordway GA, Szebeni A, Chandley MJ, Stockmeier CA, Newton S, Turecki G, Duffourc M, Zhu MY, Zhu H, and Szebeni K. Reduced gene expression of bone morphogenetic protein 7 in brainstem astrocytes in major depression. Int J Neuropsychopharmacol. Aug:15(7):855-68. (2012)

Brown RW, Noel DM, Smith JJ, Smith ML, Huggins KN, Szebeni K, Szebeni A, Duffourc M, Chandley M, Ordway, GA. Eszopiclone facilitation of the antidepressant efficacy of fluoxetine using a social defeat stress model. Pharmacol Biochem Behav. Oct:99(4):648-58. (2011)

Mandela P., Chandley M., Xu Y.-Y., Zhu M.-Y., and Ordway G.A. Reserpine-induced reduction in norepinephrine transporter function requires catecholamine storage vesicles. Neurochem. Int. 56:760-767. (2010)

Chandley M, Newell C, Wilson T, Miller M, and Miller B. Increased antibodies for the alpha7 subunit of the nicotinic receptor in schizophrenia. Schizophr Res. Apr;109(1-3):98-101. (2009)

BOOK CHAPTERS

Chandley MJ and Ordway GA. The Noradrenergic System in Depression and Suicide. In: A Concise Guide to Understanding Suicide: Epidemiology, Pathophysiology, and Prevention. (eds. Koslow, Nemeroff, and Ruiz) Cambridge University Press, Cambridge. In press.

Chandley MJ and Ordway GA. Noradrenergic Dysfunction in Depression and Suicide. In: The Neurobiological Basis of Depression and Suicide. (ed. Yogish Dwivedi) CRC press, Boca Raton. (2012)