Ph. D. Neurophysiology; Kochi Medical Graduate School, Department of Physiology,
Japan Postdoctoral Fellowship Neuroendocrinology of Obesity; McKnight Brain Institute,
Department of Neuroscience, University of Florida, USA M.SC. Medical Physiology; University of Ibadan Medical School, Department of Physiology,
Nigeria B.Med. Sc. Human Physiology; University of Port-Harcourt Medical School, Department
of Physiology, Nigeria
Human Physiology Human Anatomy Anatomy and Physiology I and II Neurology
My research program is focused on:
The molecular mechanisms and signaling pathways in the etiology of obesity syndrome
Identification of brain sites and neuroendocrine pathways for leptin action in modulating
energy and body weight homeostasis
The Hypothalamus and the control of appetite and reproduction
Otukonyong EE, Dube MG, Kalra PS, Kalra SP. Central Leptin Differentially Modulates Ultradian Secretory
Patterns of Insulin, Leptin and Ghrelin Independent of Effects on Food Intake and
Body Weight. Peptides 2005 26: 2559?2566
Otukonyong EE, Dube MG, Torto RN, Kalra PS, Kalra SP. High Fat Diet?Induced Ultradian Leptin and
Insulin Hypersecretion and Ghrelin Hyposecretion is absent in Obesity?Resistant Rats.
Obesity Research 2005; 13:6, 1?9.
Kalra SP, Bagnasco M, Otukonyong EE, Dube M, Kalra PS: Rhythmic, Reciprocal Ghrelin and leptin signalling: New Insight
in the development of Obesity (Review article). Regulatory Peptides 2003; 111: 1?11.
Okatani Y, Wakatsuki A, Otukonyong EE, Miyahara Y. Effect of prenatal melatonin exposure on gonadotropins and prolactin
secretion in male and female rat pups. Eur J Pharmacol 2001; 424: 229?235.
Otukonyong EE, Okere CO, Johnstone LE, Murata T, Kaba H, Higuchi T. Effect of suckling on NADPH?diaphorase
(Nitric oxide synthase, NOS) reactivity and NOS gene expression in the paraventricular
and supraoptic nuclei of lactating rats. Journal of Neuroendocrinology 2000; 10: 1001?8
Otukonyong EE, Okutani F, Takahashi S, Murata T, Morioka N, Kaba H, Higuchi T. Effect of food Deprivation
and leptin repletion on the plasma levels of estrogen (E2) and NADPH?d reactivity
in the ventromedial and arcuate nuclei of the hypothalamus in the female rats. Brain
Research 2000; 887: 70?9