Medical research is a vital part of the mission at the Quillen College of Medicine. Our scientists are actively researching the biological bases of medical and psychiatric disorders that reduce the quality of life of the people of our region and beyond. The faculty, staff and students of our institution are expeditiously engaged in research to develop novel treatments and cures for numerous disorders and diseases. QCOM scientists engage in research on a wide variety of medical research problems, but areas of particular focus include disorders that affect the cardiovascular system, the immune system, and the nervous system including the brain.
Another often overlooked yet critically important aspect of research at Quillen is its contribution to the education of our students. Through exposure to and engagement in our research programs, students (undergraduate, graduate, and medical students) develop their critical thinking skills, improve their ability to communicate scientific information, build self-confidence, and learn to question “medical dogma”. These important skills help them become better health professionals.
Congratulations to the Recipients of the Quillen Research Enhancement Grant Awards!
Dr. Diego Rodriguez-Gill, Principal Investigator, Department of Biomedical Sciences
Dr. Russell Brown, Co-Principal Investigator, Department of Biomedical Sciences
Project Title: Neural Plasticity Mechanisms in a Heritable Model of Drug Abuse Vulnerability
Proposed Research Project: This project is designed to analyze mechanisms of brain plasticity in response to nicotine in a novel rodent model of drug abuse vulnerability with relevance to psychosis. Across two aims, we will analyze changes in the plasticity proteins involved in both neuronal cell growth and dopamine D2 receptor signaling as well as the effects of drugs which affect potential therapeutic targets, that we have shown in past work to reduce the behavioral rewarding aspects of nicotine.
Dr. Tyrone Genade, Principal Investigator, Department of Medical Education
Dr. Patrick Bradshaw, Co-Principal Investigator, Department of Biomedical Sciences
Project Title: Study of the Cellular Effects of Fasting in Nothobranchius furzeri
Proposed Research Project: This research will determine the influence of the duration of intermittent fasting on lysosomal and proteasomal function and the accumulation of senescent cells that directly contribute to aging. This work will help determine the relative contribution to the rate of aging played by the accumulation of cellular waste, much of which is generated by reactive oxygen species-mediated damage, as well as the increased proinflammatory environment created by senescent cells.
Award Amounts: $25,000
ETSU Research Facilities
College of Medicine
- Department of Biomedical Sciences Internal Seminars
- Department of Biomedical Sciences External Seminars
College of Arts & Sciences/College of Public Health