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Department of Internal Medicine

Quillen College of Medicine

Publications, 2017-2018

EAST TENNESSEE STATE UNIVERSITY
QUILLEN COLLEGE OF MEDICINE

 SUMMARY OF SCHOLARLY ACTIVITIES

Department of Internal Medicine
July 2017 - June 2018

I. PUBLICATIONS
Journal Publications

Arikapudi, S., Rashid, S., Al Al Momani, L., Treece, J., Rashid, S., Baumrucker, S. (2017). Case Report: Serum Bovine Immunoglobulin for Chemotherapy-Induced Gastrointestinal Mucositis. American Journal of Hospice and Palliative Medicine. DOI:10.1177/1049909117735831. PMID: 29020798

Aziz SW, Aziz MH. Protective molecular mechanisms of resveratrol in UVR-inducee Skin carcinogenesis. Photodermatol Photoimmunal Photomed. 2018 Jan;34(1):35-41. PMID: 28767162

Bhogal S, Ladia V, Sitwala P, Al Balbissi K, Paul TK. Quetiapine induced myopericarditis. Am J Ther. 2017 Sep 11. doi: 10.1097/MJT.0000000000000671. [Epub ahead of print] PMID: 28953514

Bhogal S, Ladia V, Sitwala P, Cook E, Bajaj K, Ramu V, Lavie CJ, Paul TK. Cardiac Amyloidosis- An updated review with emphasis on diagnosis and future directions. Current Problems in Cardiology 2017. Curr Probl Cardiol. 2018 Jan;43(1):10-34. PMID: 29173805

Bhogal S, Mukherjee D, Banerjee S, Islam AM, Daggubati R, Paul TK. Current trends and future perspectives in the treatment of pulmonary hypertension: WHO Group II –V. Curr Probl Cardiol. 2018 May;43(5):217-231. PMID: 29153390

Bhogal S, Mukherjee D, Banerjee S, Tan W, Paul TK. Current trends and future perspectives in the treatment of pulmonary arterial hypertension. Curr Probl Cardiol. 2018 May;43(5):191-216. PMID: 29174585

Bhogal S, Pooja S, Taha Y, Papireddy M, Mahajan A, Zaidi S, Ramu V, Paul TK. Deglutition syncope: two case reports attributed to vagal hyperactivity. Case Rep Cardiol. 2017:2145678. doi: 10.1155/2017/2145678. Epub 2017 Oct 25. PMID: 29209540

Bowman, J., Treece, J., Bhattad, P., Bochis, M., & Bajaj, K. (2017). Giant left atrial myxoma masquerading as cough syncope syndrome. Journal of Investigative Medicine High Impact Case Reports. DOI:10.1177/2324709617724177 PMID: 28815190

Charilaou P, Devani K, John F, Kanna S, Ahlawat S, Young M, Khanna S, Reddy C. Acute kidney injury impact on inpatient mortality in Clostridium difficile infection: A national propensity-matched study. J Gastroenterol Hepatol 2017;4:14064. PMID: 29205514 Dai J, Kumbhare A, Williams DA, Youssef D, Yao ZQ, McCall CE, El Gazzar M. Nfia deletion in myeloid cells blocks expansion of myeloid-derived suppressor cells during sepsis. Innate Immun. 2018 Jan; 24(1):54-65. PMID: 29172874

Dai J, Kumbhare A, Youssef D, McCall CE, and El Gazzar M. Intracellular S100A9 promotes myeloid-derived suppressor cells during late sepsis. Frontiers in Immunology 2017 Nov; 8:1565.PMID:29204146

Dai J, Kumbhare A, Youssef D, Yao ZQ, McCall CE, El Gazzar M.Expression of C/EBPβ in myeloid progenitors during sepsis promotes immunosuppression. Mol Immunol. 2017 Nov; 91:165-172. PMID: 28934717

Devani K, Phemister J, Young M. Recurrent Gastrointestinal Bleeding in Young Male. 2018 Jun 6. pii: S0016-5085(18)34603-1. doi: 10.1053/j.gastro.2018.04.036. [Epub ahead of print]PMID: 29885316

Devani K, Patil N, Simons-Linares CR, Patel N, Jaiswal P, Patel P, Patel S, Savani C, Sajnani K, Young M, Reddy C. Trends in Hospitalization and Mortality of Venous Thromboembolism in Hospitalized Patients With Colon Cancer and Their Outcomes: US Perspective. Clin Colorectal Cancer 2017;16:e199-e204. PMID: 27777043

Devani K, Charilaou P, Jaiswal P, Patil N, Radadiya D, Patel P, Young M, Rockey DC, Reddy CM. Trends in Hospitalization, Acute Kidney Injury, and Mortality in Patients With Spontaneous Bacterial Peritonitis. J Clin Gastroenterol 2017 Dec 15. doi: 10.1097/MCG.0000000000000973. [Epub ahead of print]. PMID: 29252684

Geraci SA. Will cardio-virology be the next cardio-oncology? Am J Med. 2018 Feb 6. pii: S0002-9343(18)301001-1 doi: 10.1016/j.amjmed.2018.01.,023. Epub ahead of print. PMID# 29425708.

Gilotra TS, Geraci SA. C-reactive protein as an independent cardiovascular risk predictor of HIV+ patients: A focused review of published studies. J Clin Med Res. 2017 Nov;9(11):891-899. PMID 29038665.

Golla MS, Acharji S, Paul TK, Madapathi P, Garcia L. Stent graft treatment for infra-inguinal arterial disease for either in-stent restenosis and de novo lesions associated with very high rates of failure. Catheter Cardiovasc Interv. 2017 Dec 7. doi: 10.1002/ccd.27431. [Epub ahead of print]. PMID: 29214713

He Y, Guo Y, Fan C, Lei Y, Zhou Y, Zhang M, Ye C, Ji G, Ma L, Lian J, Moorman JP, Yao ZQ, Wang J, Hao C, Zhang Y, Jia Z Interferon-α-Enhanced CD100/Plexin-B1/B2 Interactions Promote Natural Killer Cell Functions in Patients with Chronic Hepatitis C Virus Infection. Front Immunol. 2017 Nov 3;8:1435. PMID: 29163508

Hicks A, Leicht S, Youngberg GA Bullous Pemphigoid: Use of C4d Immunofluorescent Staining in a Case With Repeated Negative Conventional Direct Immunofluorescence Studies.Kassaby SS,.Am J Dermatopathol. 2017 Dec;39(12):932-934. doi:10.1097/DAD.0000000000000943.PMID:28654468

Ibrahim M, Nunley DL. Two Catastrophes in One Patient: Drup Reaction with Eosinophilia and Systemic Symptoms and Toxic Shock Synfrome. Cureus. 2017 Jun 15;9(6):e1359. Doi: 10.7759/cureus. 1359. PMID: 28721327

ISiedlecki J, Reiterer V, Leicht S, Foerster P, Kortüm K, Schaller U, Priglinger S, Fuerweger C, Muacevic A, Eibl-Lindner K. Incidence of secondary glaucoma after treatment of uveal

melanoma with robotic radiosurgery versus brachytherapy. 2017 Dec;95(8):e734-e739. doi: 10.1111/aos.13418. PMID: 28387434

Joslyn JA, Khattak FH, Geraci SA. A case of a reversible neurologic adverse reaction to apixaban confirmed by re-challenge. J Clin Med Res. 2018;10(6):523-526. PMID: 29707095

Khalid M, Khattak F, Murtaza G, Paul TK. Takotsubo cardiomyopathy Mimicking Stent Thrombosis after Percutaneous Coronary Intervention. J Investig Med High Impact Case Rep. PMID: 29761112

Khalid M, Khattak F, Ramu V. Cardiovascular Side Effects of Tyrosine Kinase Inhibitor Ibrutinib (Imbruvica) and Interaction with Direct Oral Anticoagulant. American journal of therapeutics. 2018 Jun 18. doi: 10.1097/MJT.0000000000000775. PMID: 29916856

Khalid M, Murtaza G, Ayub M, Ramu V, Paul TK. Right ventricle perforation post pacemaker insertion complicated with acute pericardial effusion and cardiac tamponade physiology. Cureus March 2018;10(3):e2266. PMID: 29736351

Khalid M, Khan I, Rahman Z, Alazzeh A, Youssef D. Fibrosing Mediastinitis: Uncommon Life-threatening Complication of Histoplasmosis. Cureus 10(4):e2 532. Doi:10.7759/cureus.2532 (April 25, 2018). PMID: 29946500

Khalik MF, Aziz SW. Endocrinopathies Related to Immne Checkpoint Inhibitors. AmericanJournal of Therapeutices. Jun 25 2018 PMID: 29965803 Lewis PO, Khan I, Patel P. Ann Pharmacotherapy. Rifampin-Resistant Staphylococcus aureus Bacteremia in a Patient on Chronic Rifaximin. 2017 Jul;51(7):617-618. doi:10.1177/1060028017701221. Epub 2017 Mar 20. PMID: 28622735

Lewis PO, Khan I, Patel P. Successful stepdown treatment of pulmonary Histoplasmosis with thrice-weekly liposomal amphotericin B in a hospital associated, outpatient infusion center: A case report. Journal of Clinical Pharmacy and Therapeutics 2018 (April):269-2. PMID: 28806478

Liu H, Liu P, Shi X, Yin D, Zhao J. NR4A2 protects cardiomyocytes against myocardial infarction injury by promoting autophagy. Cell Death Discov. 2018 Feb 15;4:27. PMID: 29531824

Macmillan P, Geraci SA. (N/A) Culture Shift: Building an awareness of our mortality. Cureus. 2017; 9(12): e1969. doi:10.7759/cureus.1969. PMID# 29492358.

Mamudu H, Jones A, Paul TK, Subedi P, Wang L, Alamian A, Alamin A, Blackwell G, Budoff M. Geographic and individual correlates of subclinical atherosclerosis in asymptomatic rural Appalachian population. Am J Med Sci 2018; 355(2):140-148. PMID: 29406041

McPeak MB, Youssef D, Williams DA, Pritchett CL, Yao ZQ, McCall CE, El Gazzar M. Frontline Science: Myeloid cell-specific deletion of Cebpb decreases sepsis-induced immunosuppression in mice. J Leukoc Biol. 2017 Aug; 102(2):191-200. PMID: 28476751

Moore CA, Khalid MF, Patel P, Goldstein JS. Aeromonas salmonicida Bacteremia after Drinking Well Water in an Immunocompetent Patient. J Glob Infect Dis. 2017 Apr-Jun;9(2):82-84. doi: 10.4103/jgid.jgid_147_16. PMID: 28584462

Nguyen KPL, Pai V, Rashid S, Treece J, Moulton M, Baumrucker SJ. Prognostication in Anoxic Brain Injury. American Journal of Hospice and Palliative Medicine. 2018 Jan 1:1049909118767881. doi:10.1177/1049909118767881. PMID: 29614864 Onweni C, Balagoni H, Treece J, Addo Yobo E, Patel A, Phemister J, Srinath M, Young M Autoimmune Pancreatitis Type 2: Case Report Journal of investigative Medicine. 2017 Oct 10;5(4):2324709617734245. doi: 10.1177/2324709617734245. eCollection 2017 Oct-Dec. PMID: 29051892

Papireddy M, Lavie CJ, Deoker A, Mamudu H, Paul TK. New algorithm for the prediction of cardiovascular risk in symptomatic adults with stable chest pain. Curr Cardiol Rep 2018 Mar 24;20(5):30. PMID: 29574581.

Patel A, Al-Balbissi K, Haldis T, Paul TK. Neo-left main channel creation using double stenting alongside a Sapien 3 aortic valve bioprosthesis for left main coronary obstruction following valve-in-valve transcatheter aortic valve implantation. J Investig Med High Impact Case Rep. 2018 Mar 30;6:2324709618767696. doi: 10.1177/2324709618767696. PMID: 29623280

Paul TK, Bhatheja S, Panchal HB, Zheng S, Banerjee S, Rao SV, Guzman L, Beohar N, Zhao D, Mehran R, Mukherjee D. Outcomes of saphenous vein graft intervention with and without embolic protection device: A Comprehensive Review and Meta-Analysis. Circ Cardiovasc Interv. 2017;10:e005538. DOI: 10.1161/CIRCINTERVENTIONS.117.005538. PMID: 29246912

Ren JP, Wang L, Zhao J, Wang L, Ning S, El Gazzar M, Moorman JP, Yao ZQ. Decline of miR-124 in myeloid cells promotes regulatory T-cell development in hepatitis C virus infection. Immunology. 2017. 150(2):213-220. PMID: 27753084

Ren JP, Wang L, Zhao J, Wang L, Ning SB, El Gazzar M, Moorman JP, Yao ZQ. Decline of miR-124 in myeloid cells promotes regulatory T-cell development in hepatitis C virus infection. Immunology. 2017 Feb; 150(2):213-220. PMID: 27753084

Sethi P, Panchal H, Veeranki SP, Mamudu H, Rahman, Z, Paul TK. Diagnostic value of non-invasive computed tomography perfusion imaging for assessing hemodynamically significant native coronary artery lesion: A meta-analysis. Am J Med Sci. 2017 Sep;354(3):291-298. doi: 10.1016/j.amjms.2017.03.016. Epub 2017 Mar 12. PMID: 28918837

Sethi P, Treece J. Onweni C, Pai V, Arikapudi S., Kallur L, Kohli, V, Moorman J. (2017). Acute Kidney Injury, Immune Thrombocytopenic Purpura, and the Infection That Binds Them Together: Disseminated Histoplasmosis. Journal of Investigative Medicine High Impact Case Reports. DOI:10.1177/2324709617746193. PMID:29276711

Sethi, P., Treece, J, Pai, V., Onweni, C., Rahman, Z, & Singh, S. (2017). The Mystery of Multiple Masses: Case Report of Anaplastic Astrocytoma. Cureus, DOI:10.7759/cureus.1384. PMID:2875924

Sethi, P., Treece, J., Onweni, C. (2017). Sudden Collapse in First Trimester: Report of Hyperacute Renal Failure Secondary to Collapsing Glomerulopathy as the Initial Presentation of Lupus. Cureus. DOI:10.7759/cureus.1509. PMID:28948129

Sethi, P., Treece, J., Onweni, C., Pai, V. (2017). Antidote or Poison: A Case of Anaphylactic Shock After Intra Articular Corticosteroid Injection. Cureus. 9(8): e1625. DOI:10.7759/cureus.1625. PMID:28998135

Sethi, P., Treece, J., Onweni, C., Pai, V., Rahman, Z, & Singh, S. (2017). The Importance of a Complete Differential: Case Report of a Tuberculoma in a Patient without Pulmonary Involvement, Cureus, DOI:10.7759/cureus.1405. PMID:28852602

Sethi, P., Treece, J., Pai, V., Onweni, C. (2017). Long QT Syndrome - Unveiled by a Fatal Combination of Medications and Electrolyte Abnormalities. Cureus. 9(8): e1581. DOI:10.7759/cureus.158. PMID:29057193

Shi X, Li W, Liu H, Yin D, Zhao J. The ROS/NF-κB/NR4A2 pathway is involved in H2O2 induced apoptosis of resident cardiac stem cells via autophagy. Oncotarget. 2017 Sep 8;8(44):77634-77648. PMID:29100414

Shi X, Li W, Liu H, Yin D, Zhao J. β-Cyclodextrin induces the differentiation of resident cardiac stem cells to cardiomyocytes through autophagy. Biochim Biophys Acta. 2017 Aug;1864(8):1425-1434. PMID:28522298

Treece J, Chemchirian H, Hamilton N, Jbara M, Gangadharan V, Paul TK, Baumrucker SJ. A review of prognostic tool in heart failure. Am J Hosp Palliat Care. 2018 Mar;35(3):514-522. PMID:28554221

Ugoeke, N., Onweni, C., Treece, J., Pai, V., Kulbacki, E., DaSilva, M., Bajaj, K. (2017). Inflammatory Breast Cancer and Warm Antibody Autoimmune Hemolytic Anemia: A Rare Paraneoplastic Syndrome. Journal of Investigative Medicine High Impact Case Reports. 2017 Oct-Dec; 5(4). DOI:10.1177/2324709617740905. PMID:29164157

Wang L, Howell M, McPeak B, Riggs K, Kohne C, Yohanon J.-U., Foxler DE, Sharp TV, Moorman JP, Yao ZQ, Ning S. LIMD1 is induced by and required for LMP1 signaling, and protects EBV-transformed cells from DNA damage-induced cell death. 2017. 9(5):6282-6297. DOI: doi.org/10.18632/oncotarget.23676. PMID:29464072

Wang L, Howell M, McPeak B, Riggs K, Kohne C, Yohanon J.-U., Foxler DE, Sharp TV, Moorman JP, Yao ZQ, Ning S. LIMD1 is induced by and required for LMP1 signaling, and protects EBV-transformed cells from DNA damage-induced cell death. 2017. 9(5):6282-6297. DOI: doi.org/10.18632/oncotarget.23676 PMID: 29464072.

Wang L, Ning S. "Toll-free" pathways for production of type I interferons. AIMS Allergy and Immunology. 2017. 1(3): 143-163. Free full text PDF. PMID: 29202128

Wang L, Ren J, Li G, Moorman JP, Yao ZQ, Ning S. LMP1 Signaling Pathway Activates IRF4 in Latent EBV Infection and A Positive Circuit between PI3K and Src Is Required. Oncogene. 2017. 36(16):2265-2274. PMID: 27819673

Wang L, Wang Y, Zhao J, Ren J, Hall KH, Moorman JP, Yao ZQ, Ning S. The Linear Ubiquitin Assembly Complex Modulates Latent Membrane Protein 1 Activation of NF-κB and Interferon Regulatory Factor 7. J Virol. 2017 Jan 31;91(4). pii: e01138-16. PMID:27903798

Yi W, Zhang P, Liang Y, Zhou Y, Shen H, Fan C, Moorman JP, Yao ZQ, Jia Z, Zhang Y. T-bet-mediated Tim-3 expression dampens monocyte function during chronic hepatitis C virus infection. Immunology. 2017 Mar;150(3):301-311. PMID:27809352

Zhang H, Caudle Y, Shaikh A, Yao B, Yin D. Inhibition of microRNA-23b prevents polymicrobial sepsis-induced cardiac dysfunction by modulating TGIF1 and PTEN. Biomed Pharmacother. 2018 Apr 21;103:869-878 PMID:29710503

Zhang H, Caudle Y, Wheeler C, Zhou Y, Stuart C, Yao B, Yin D. TGF-β1/Smad2/3/Foxp3 signaling is required for chronic stress-induced immune suppression. Journal of Neuroimmunology. 2018 Jan 15;314:30-41. PMID:29169800

Zhang H, Li H, Shaikh A, Caudle Y, Yao B, Yin D. Inhibition of MicroRNA-23b Attenuates Immunosuppression in Late Sepsis through NIK, TRAF1 and XIAP. Journal of Infectious Diseases. 2018 Mar 1. doi: 10.1093/infdis/jiy116.PMID:29506272

Zhao J, Dang X, Zhang P, Nguyen LN, Cao D, Wu XY, Morrison Z, Zhang Y, Jia Z, Xie Q, Wang L, Ning S, El Gazzar M, Moorman JP, and Yao ZQ. Insufficiency of DNA repair enzyme ATM promotes naïve CD4 T cell loss in chronic hepatitis C virus infection. Cell Discovery 2018 Apr; 4: 16. PMID:29644094

Zhou J*, Yang X*, Ning S*, Wang L, Wang K, Zhang Y, Yuan F, Li F, Zhuo D, Tang L, Zhuo D. Identification of KANSARL as the First Cancer Predisposition Fusion Gene Specific to the Population of European Ancestry Origin. Oncotarget. 2017. 8(31):50594-50607. PMCID: PMC5584173 (Highlighted at RNA-Seq blog). * Contributed equally to this project. PMID: 28881586

Zhou Y, Li H, Siddiqui N, Caudle Y, Zhang H, El Gazzar M, and Yin D. Hematopoietic stem progenitor cells prevent chronic stress-induced lymphocyte apoptosis. Journal of Neuroimmunology 2017 Aug; 309:72-76.

Zhou Y, Li H, Siddiqui N, Caudle Y, Zhang H, Elgazzar M, Yin D. Hematopoietic stem progenitor cells prevent chronic stress-induced lymphocyte apoptosis. Journal of Neuroimmunology. 2017 Aug 15;309:72-76. PMID:28601292

II. PUBLISHED PAPERS, ABSTRACTS AND/OR POSTER PRESENTATIONS

Al Momani, L., Arikapudi, S., Gaddam, S., Treece, J., Rashid, S., Baumrucker, S. (2017). Home-Based Treatment for Chronic Constipation. Home Health Care Management & Practice. https://doi.org/10.1177/108482231774640 http://journals.sagepub.com/doi/abs/10.1177/1084822317746403?journalCode=hhcb

Bhogal, S., Khraisha, O., Al Madani, M., Treece, J., Baumrucker, S. J., Paul, T. (2018). Emergence of Sildenafil as a Treatment of Pulmonary Arterial Hypertension and its Role as a Palliative Therapy. American Journal of Therapeutics.

Carrillo-Martin I, Molony K, Reddy K, Youssef D, Gonzalez-Estrada A. PO31 A case of cefepime IgE-mediated reaction with negative skin testing, should current concentrations by reconsidered? Allergy Asthma & Immunol (Official publication of the American College of Allergy, Asthma & Immunology) Nov 2017; 119(5):S26. Gunter BR, Butler KA, Wallace RL, Smith SM, Harirforoosh S. NSAIDs-Induced Cardio- and Cerebro-vascular Adverse Events: a Meta-analysis Journal of Clinical Pharmacy and Therapeutics DOI:10.1111/jcpt.12484

Khalid M, Murtaza G, Albalbissi A, Bochis M, Paul TK. Acute limb ischemia due to cardiac thromboembolismin a young patient without myocardial infarction or cardiomyopathy. Cardiology and Angiology: An International Journal 2018;7(3):1-5.

Khattak F, Alam MB, Paul TK, Shasank R, Wazir S, Lavie CJ, Samir S. Anticoagulation in non-valvular atrial fibrillation: Consensus and Challenges. Am J Med Sci 2018. In Press.

Mungo N, Youssef D, Youngberg G, Gonzalez-Estrada A. PO25 An unusual case of voriconazole induced pseudoporphyria. Ann Allergy Asthma Immunol (Official publication of the American College of Allergy, Asthma & Immunology) Nov 2017; 119(5):S25.

Dai J, Kumbhare A, Youssef D, McCall CE, El Gazzar M. Intracellular S100A9 Promotes Myeloid-Derived Suppressor Cells during Late Sepsis. Front Immunol 2017 Nov 17; 8:1565. Doi: 10.3389/fimmu.2017.01565.

Kallur L, Asberry D, Youssef D, El Abbassi A. Endobronchial Lipoma Presenting as Recurrent Bronchitis and the Therapeutic Role of Argon Plasma Coagulation. Chest 2017; Oct; 152(4):A852.

Kallur L, Bentley NK, El-Abbassi A, Youssef D. Metapneumovirus Pneumonia. Am J Respir Crit Care Med. 2017; (1_MeetingAbstracts): A5865.

Kallur L, Karakattu S, Green J, Youssef D, El Abbassi A. Gravel in My Lungs: Utilizing Cryotherapy for Broncholithiasis Extraction. Chest 2017; Oct; 152 (4):A852.

Khan I, Khalid M, Moorman J, Ibrahim L, Youssef D. Interesting Case of Leptospirosis presenting as jaundice and acute renal failure in North East Tennessee. J Microbiol Infect Dis. 2018 April 10 (accepted). Lewis PO, Khan I, Patel P. Ann Pharmacotherapy. 2017 Jul;51(7):617-618. doi:10.1177/1060028017701221. Epub 2017 Mar 20. Rifampin-Resistant Staphylococcus aureus Bacteremia in a Patient on Chronic Rifaximin.

Ning S. Wang L*. Identification of PP1 as the First Phosphatase for IRF7. Journal of Cell Signaling. 2017. 2: 146. Full-text PDF.

Onweni, C., Treece, J., Moore, C., & Rogers, M. (2017). Case Report: Fever of Unknown Origin – An Unusual Presentation for Diffuse Large B-Cell Lymphoma. Journal of Cancer Therapy, 8, 405-412. DOI:10.4236/jct.2017.84035

Sitwala, P., Treece, J., Bhattad, V., Ladia, V., Counts, M., Helton, T.J. (2018). Radial Artery Pseudoaneurysm - An uncommon vascular complication of transradial heart catheterization. Journal of Investigative Medicine High Impact Case Reports.

Treece JM, MD, Al Madani M, El Khoury G, Khraisha O, Paul TK. Methadone: The Potential Palliative Killer. J Pharmacol Pharmacother. In press.

Treece, J., Al Madani, M., El Khoury, G., Khraisha, O., Baumrucker, S., Paul, T. Comprehensive review on Methadone induced QT prolongation and Torsades – A Potential killer. Journal of Pharmacology and Pharmacotherapeutics.

Treece, J., Ghouse, M., Rashid, S., Arikapudi, S., Sankhyan, P., Kohli, V., O’Neill, L., Addo-Yobo, E., Bhattad, V., Baumrucker, S. (2018). The Effect of Hospice on Hospital Admission and Readmission Rates: A Review. Home Health Care Management & Practice.

Treece, J., Josan, E., Tawadros, F. (2017). Asystole due to Spontaneous Hemopericardiac Tamponade in a Patient on Warfarin. American Journal of Therapeutics. DOI:10.1097/MJT.0000000000000612

Zhou Y, Song Y, Shaikh Z, Li H, Zhang H, Caudle Y, Zheng S, Yan H, Hu D, Stuart C, Yin D. Attenuation of cardiac dysfunction in late sepsis by microRNA-155 is mediated via targeting of JNK and β-arrestin 2 expression. Oncotarget. 2017 Jul 18;8(29):47317-47329.

III. EDITORIALS, WEB PAGES, LETTERS, WHITE PAPERS, Other (Non-Peer-Reviewed)

 

IV. INVITED PRESENTATIONS

Paul TK. A rare case of large coronary perforation post stenting without any hemodynamic compromise. Cardiovascular Innovation Conference, August 2017, Denver, CO.

 

V. PEER REVIEW

William Stone, Victoria Palau Koyamangalath Krishnan, Chapter title: A systems medicine approach to the role of vitamins in protecting the gastrointestinal tract from oxidative stress. In: 1st Edition Oxidative Stress and Dietary Antioxidants, Editors Jordi Gracia-Sancho M. Salvadó, ISBN: 9780128053775 Academic Press, 24th May 2017

 

VI. EXTRAMUAL FUNDING

Patient Centered Outcomes Research Institute (PCORI)
Grant # EAIN-4411 Co-Lead Investigator: Timir Paul
06/2017-05/2019
Project: Developing a research hypothesis to prevent and control cardiovascular diseases in
Central Appalachia
Awarded $250,000.00

“Role of hematopoietic stem progenitor cells in stress-induced apoptosis” NIH
Principal Investigator: Deling Yin
Agency: National Institutes of Health/National institute of General Medical Sciences
Period: 04/01/2015 – 03/31/2018
The major goals of this project are to 1) define the role of hematopoietic stem progenitor cells (HSPCs) in stress-induced immune suppression; 2) investigate the effect of HSPCs on IL-4-mediated apoptotic signaling following stress.
Role: PI
Total: $338,539.

LIMD1 Is a Novel Marker Associated with IRF4 in EBV Latency and Lymphoma
1R15DE027314-01 Shunbin Ning
07/01/2017-06/30/2020
Agency: National Institutes of Health To investigate the regulation and role of the LIM-domain-containing protein LIMD1 in LMP1 signaling transduction and oncogenesis.
Role: Co-Principal Investigator (30% efforts)
Total costs: $444,000.00; Direct costs: $300,000.00

Targeting IRF4 in AIDS-related Viral Lymphomas
1R15DE026399-01A1 Shunbin Ning
04/01/2017-03/31/2020
Agency: National Institutes of Health To investigated the regulation and role of IRF4 in EBV-associated lymphomas
Role: Principal Investigator (20% efforts)
Total costs: $444,000.00; Direct costs: $300,000.00

Linear ubiquitination and LMP1-mediated oncogenesis
1R15DE026126-01A1 (Shunbin Ning)
10/01/2016-09/30/2019
Agency: National Institutes of Health To investigate the role of LUBAC-triggered linear ubiquitination in LMP1 signaling and oncogenesis.
Role: Principal Investigator (20% efforts)
Total costs: $444,000.00; Direct costs: $300,000.00

 

Ongoing Grants

Tim-3-mediated IL-12 dysregulation in antiviral responses to HCV infection
NIH/NIDDK R01DK09526: PI – Yao, John
04/01/2012 - 03/31/2018
Agency: National Institutes of Health
Total Costs: $1.4 million
Co PI: Moorman, Jonathan 

miR181a-mediated premature T cell aging in vaccine failure in viral infection
NIH/NIAID R01 R01AI114748 PI – Yao, John
12/01/2014 - 11/30/2019
Agency: National Institutes of Health
Total Cost: $1,825,000
Co PI: Moorman, Jonathan

The role of microRNAs in premature T cell aging during HIV infection
NIH/NIAID R15: PI – Moorman, Jonathan
05/01/2015 - 04/30/2018
Agency: National Institutes of Health
Co PI: Yao, John 

NIH/NIAID R01 R01AI114748-01
Yao (PI) /Moorman (co-PI) 12/01/2014 ~ 11/30/2019
Title: miR181a-mediated premature T cell aging in vaccine failure during viral infection
The goal of this study is to elucidate the mechanism of how chronic viral infection induces premature T cell aging and vaccine failure through a miR181a-mediated regulation. 

NIH/NIAID R21 R21AI138598-01A1
Yao (PI) /Moorman (co-PI) 06/21/2018-05/31/2019
Title: Telomere loss and T cell aging in HBV vaccine response in HIV-Infected individuals
The goal of this project is examine the role of the loss of telomeres in HIV-infected individuals in relation to poor vaccine responses to hepatitis

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